John E Pascoe , Alexander Zygmunt , Zarmina Ehsan , Neepa Gurbani
{"title":"Sleep in pediatric neuromuscular disorders","authors":"John E Pascoe , Alexander Zygmunt , Zarmina Ehsan , Neepa Gurbani","doi":"10.1016/j.spen.2023.101092","DOIUrl":null,"url":null,"abstract":"<div><p>Sleep disordered breathing<span><span> (SDB) is prevalent among children with neuromuscular disorders<span> (NMD). The combination of respiratory muscle weakness, altered drive, and chest wall distortion due to </span></span>scoliosis<span> make sleep a stressful state in this population. Symptomatology<span><span><span><span><span> can range from absent to snoring, nocturnal awakenings, morning headaches, and excessive daytime sleepiness. </span>Sequelae of untreated SDB includes </span>cardiovascular effects, metabolic derangements, and neurocognitive concerns which can be compounded by those innate to the NMD. The clinician should have a low threshold for obtaining </span>polysomnography and recognize the nuances of individual disorders due to disproportionately impacted muscle groups such as </span>hypoventilation<span> in ambulating patients from diaphragm weakness. Non-invasive or invasive ventilation<span> are the mainstay of treatment<span>. In this review we explore the diagnosis and treatment of SDB in children with various NMD.</span></span></span></span></span></span></p></div>","PeriodicalId":49284,"journal":{"name":"Seminars in Pediatric Neurology","volume":"48 ","pages":"Article 101092"},"PeriodicalIF":2.4000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in Pediatric Neurology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S107190912300061X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Sleep disordered breathing (SDB) is prevalent among children with neuromuscular disorders (NMD). The combination of respiratory muscle weakness, altered drive, and chest wall distortion due to scoliosis make sleep a stressful state in this population. Symptomatology can range from absent to snoring, nocturnal awakenings, morning headaches, and excessive daytime sleepiness. Sequelae of untreated SDB includes cardiovascular effects, metabolic derangements, and neurocognitive concerns which can be compounded by those innate to the NMD. The clinician should have a low threshold for obtaining polysomnography and recognize the nuances of individual disorders due to disproportionately impacted muscle groups such as hypoventilation in ambulating patients from diaphragm weakness. Non-invasive or invasive ventilation are the mainstay of treatment. In this review we explore the diagnosis and treatment of SDB in children with various NMD.
期刊介绍：
Seminars in Pediatric Neurology is a topical journal that focuses on subjects of current importance in the field of pediatric neurology. The journal is devoted to making the status of such topics and the results of new investigations readily available to the practicing physician. Seminars in Pediatric Neurology is of special interest to pediatric neurologists, pediatric neuropathologists, behavioral pediatricians, and neurologists who treat all ages.
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