Rapid artificial ventricular pacing for thoracic endovascular aortic repair

Mehmet Cahit Saricaoglu, Levent Yazicioglu
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Abstract

Aim: Rapid artificial ventricular pacing (RAVP) is a reproducible method for rapid and reversible reduction of transvascular flow during endovascular procedures. This method has the potential to increase patient tolerance, reduce operation duration, infection risk, X-ray dose and facilitate early patient mobilisation. The aim of this study to compare the efficacy, safety and impact of RAVP and pharmacological-induced hypotension in patients who underwent thoracic endovascular aortic repair (TEVAR) procedures for aortic dissection and aneurysm. Material and Methods: This retrospective, observational, case-control study was conducted between January 2014 and December 2022. The adult patients who underwent TEVAR procedures for aortic dissection and aneurysm were enrolled in this study. Mean arterial pressure, heart rate, total operation duration, incidence of endoleak, duration of intensive care unit-hospitalization stay, and hospital mortality ratio were compared between nitroglycerin induced hypotension group and RAVP group. Results: A total of 279 patients who underwent TEVAR procedures were included in this study. The mean age of patients in this cohort was 65.6±5.7 years and 158 (56.6%) of the patients were male. Of these 279 patients, hypotension during stent-graft was achieved with nitroglycerin in 155 patients. There were no statistical differences between these two groups in terms of age, gender, body mass index, comorbidities and drugs. The blood pressure lowering effect and the heart rate during the intervention was significantly higher in RAVP. Endoleak and hospital mortality rates were similar in each group. Conclusion: RAVP is a feasible and safe method because it paves the way for agile maneuvers to maintain optimal hemodynamic conditions. Besides this, more meticulous, accurate deployment of endograft can be established with RAVP.
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快速人工心室起搏用于胸腔血管内主动脉修复
目的:快速人工心室起搏(RAVP)是一种可重复的方法,可快速和可逆地减少血管内手术过程中的经血管血流。这种方法有可能增加患者的耐受性,减少手术时间,感染风险,x射线剂量并促进患者早期活动。本研究的目的是比较RAVP和药理学诱导的低血压对因主动脉夹层和动脉瘤接受胸腔血管内主动脉修复(TEVAR)手术的患者的疗效、安全性和影响。材料和方法:这项回顾性、观察性、病例对照研究于2014年1月至2022年12月进行。接受TEVAR手术治疗主动脉夹层和动脉瘤的成年患者被纳入本研究。比较硝酸甘油致低血压组和RAVP组的平均动脉压、心率、总手术时间、内漏发生率、重症监护病房-住院时间、住院死亡率。结果:279例接受TEVAR手术的患者被纳入本研究。该队列患者的平均年龄为65.6±5.7岁,其中158例(56.6%)为男性。在这279例患者中,155例患者在支架移植期间使用硝酸甘油实现了低血压。两组患者在年龄、性别、体重指数、合并症及用药方面无统计学差异。RAVP组在干预期间的降压效果和心率显著高于RAVP组。两组患者的肠道死亡率和住院死亡率相似。结论:RAVP是一种可行且安全的方法,为灵活机动保持最佳血流动力学条件铺平了道路。除此之外,利用RAVP可以建立更细致、准确的内移植物部署。
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