Anthracycline-induced cardiotoxicity in a child with acute lymphoblastic leukaemia against the background of new coronavirus infection

G. V. Kondratiev, M. E. Melnikov, S. A. Kulyova, A. S. Chepelev, S. L. Bannova, T. L. Kornishina, I. A. Reshetnyak, K. D. Murasheva
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Abstract

Anthracycline chemotherapy drugs are widely used for the treatment of various tumors but they are associated with high cardiotoxicity. The novel coronavirus disease can also negatively affect the heart function. In this article, we report a case of anthracycline-related cardiotoxicity in a child with refractory acute lymphoblastic leukemia and the novel coronavirus disease, describing changes in instrumental and laboratory parameters observed over time during the treatment and providing a description of autopsy samples of the myocardium. The patient’s parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.
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新型冠状病毒感染背景下蒽环类药物引起的急性淋巴细胞白血病患儿心脏毒性
蒽环类化疗药物广泛用于各种肿瘤的治疗,但其具有较高的心脏毒性。新型冠状病毒也会对心脏功能产生负面影响。在这篇文章中,我们报告了一例难治性急性淋巴细胞白血病和新型冠状病毒疾病患儿的蒽环类药物相关心脏毒性,描述了在治疗期间观察到的仪器和实验室参数的变化,并提供了心肌解剖样本的描述。患者的父母同意使用他们孩子的数据,包括照片,用于研究目的和出版物。
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来源期刊
Pediatric Hematology/Oncology and Immunopathology
Pediatric Hematology/Oncology and Immunopathology Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.40
自引率
0.00%
发文量
49
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