The efficacy of endoscopic endonasal duraplasty compared to transcranial duraplasty for post-traumatic CSF rhinorrhea in terms of CSF rhinorrhea recurrence and other complications

Pranab Regmi, Ahtesham Khizar, Pradhumna Kumar Yadav
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Abstract

Objectives. To determine the efficacy of endoscopic endonasal dura repair versus transcranial dura repair for post-traumatic CSF rhinorrhoea in terms of CSF rhinorrhea recurrence and other complications. Materials and methods. A total of 92 patients (age 15-50 years, both genders) with an established diagnosis of CSF rhinorrhea following traumatic brain injury were enrolled in this prospective cohort study. Group A and Group B were formed from the patients. Group A received endoscopic endonasal duraplasty, while Group B received transcranial duraplasty. Recurrence of CSF rhinorrhea, as well as any other complications (meningitis, anosmia, hydrocephalus, and abscess), were noted and compared between the two groups one week, two weeks, and four weeks after the procedure. Results. In Group A, the mean age was 28.6 ± 9.9 SD years and in Group B it was 29.9 ± 8.6 SD years. In group A, there were 63% (n=29/46) patients who had age between 15-30 years and 37% (n=17/46) had age between 31-50 years. In group B, 52.2% (n=24/46) patients had age between 15-30 years and 47.8% (n=22/46) had age between 31-50 years. In group A, there were 82.6% (n=38/46) males and 17.4% (n=8/46) were females and in group B there were 87% (n=40/46) males and 13% (n=6/46) females. At one month follow-up, overall recurrence of rhinorrhea was observed in 17.4% (n=8/46) patients in Group A, while it was 41.3% (n=19/46) patients in Group B (P=0.012). On the other hand, overall complications were 8.7% (n=21/46) in Group A patients, while they were 45.7% (n=21/46) in Group B patients (P=0.001). Conclusions. During a one-month follow-up, patients who received endoscopic repair experienced fewer recurrences and other complications overall than patients who underwent transcranial duraplasty, and the difference was statistically significant. We advise conducting studies with a larger sample size and longer follow-up periods.
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内镜下鼻内硬脑膜成形术与经颅硬脑膜成形术治疗创伤后脑脊液鼻漏在脑脊液鼻漏复发及其他并发症方面的疗效比较
目标。比较经颅硬脑膜修复术与鼻内镜硬脑膜修复术治疗外伤性脑脊液鼻漏复发及其他并发症的疗效。材料和方法。这项前瞻性队列研究共纳入了92例确诊为外伤性脑损伤后脑脊液鼻漏的患者(年龄15-50岁,男女均可)。A组和B组由患者组成。A组行鼻内镜下硬脑膜成形术,B组行经颅硬脑膜成形术。观察两组患者术后1周、2周和4周脑脊液鼻漏的复发情况,以及其他并发症(脑膜炎、嗅觉丧失、脑积水和脓肿)。结果。A组患者平均年龄28.6±9.9 SD年,B组患者平均年龄29.9±8.6 SD年。在A组中,63% (n=29/46)的患者年龄在15-30岁之间,37% (n=17/46)的患者年龄在31-50岁之间。B组有52.2% (n=24/46)的患者年龄在15-30岁之间,47.8% (n=22/46)的患者年龄在31-50岁之间。A组男性占82.6% (n=38/46),女性占17.4% (n=8/46); B组男性占87% (n=40/46),女性占13% (n=6/46)。随访1个月,A组鼻漏总复发率为17.4% (n=8/46), B组为41.3% (n=19/46) (P=0.012)。A组总并发症发生率为8.7% (n=21/46), B组总并发症发生率为45.7% (n=21/46) (P=0.001)。结论。在一个月的随访中,接受内窥镜修复的患者总体上比接受经颅硬膜成形术的患者复发和其他并发症更少,差异有统计学意义。我们建议进行更大样本量和更长的随访期的研究。
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