Affected cortico-striatal-cerebellar network in schizophrenia with catatonia revealed by magnetic resonance imaging: indications for electroconvulsive therapy and repetitive transcranial magnetic stimulation

Xiao-Fan Liu, Shu-Wan Zhao, Zachary Kratochvil, Jia-Cheng Jiang, Di Cui, Lu Wang, Jing-Wen Fan, Yue-Wen Gu, Hong Yin, Jin-Jin Cui, Xiao Chang, Long-Biao Cui
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Abstract

Abstract Catatonia is a psychomotor syndrome that can occur in a broad spectrum of brain disorders, including schizophrenia. Current findings suggest that the neurobiological process underlying catatonia symptoms in schizophrenia is poorly understood. However, emerging neuroimaging studies in catatonia patients have indicated that a disruption in anatomical connectivity of the cortico-striatal-cerebellar system is part of the neurobiology of catatonia, which could serve as a target of neurostimulation such as electroconvulsive therapy and repeated transcranial magnetic stimulation.
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磁共振成像显示精神分裂症伴紧张症的皮质纹状体小脑网络受影响:电痉挛治疗和重复经颅磁刺激的适应症
紧张症是一种精神运动综合征,可发生在广泛的脑部疾病,包括精神分裂症。目前的研究结果表明,精神分裂症紧张症症状背后的神经生物学过程尚不清楚。然而,新兴的紧张症患者神经影像学研究表明,皮质-纹状体-小脑系统解剖连通性的破坏是紧张症神经生物学的一部分,可以作为神经刺激的靶点,如电休克治疗和反复经颅磁刺激。
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