The Role of Comorbid Conditions and Socioeconomic Factors in Mortality for Patients Hospitalized with COVID-19

Roberta Redfern, Camelia Arsene, Lance Dworkin, Shipra Singh, Amala Ambati, Lukken Imel, Alexandria Williamson, Sadik Khuder
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Abstract

Background: The emergence of COVID-19 as a global pandemic has provided yet another example of how racial and social factors can exacerbate health disparities and disproportionately affect minority populations. The goal of the current study was to understand how some of these factors impacted survival in patients hospitalized with COVID-19 in Northwest Ohio during the first year of the pandemic.Methods: This study was a retrospective review of patient data from a single health care system. Electronic medical records were queried to obtain information on patients who were admitted to the hospital and had a laboratory-confirmed COVID-19 infection during their admission. Different predictors were included in the final Cox proportional hazard regression model.Results: There were 3468 patients included in the analyses with an all -cause mortality rate of 18.5%. On average, White patients were older on admission with higher rates of mortality than patients who were Black or of “Other” races (19.8% versus 12.5% and 11.0%, respectively, p < .001). Mortality rates varied significantly by insurance status, with the highest mortality rates observed in the Medicare and “Other” categories (27.1% and 16.5%, respectively). Cox proportional hazard regression model also found race and insurance status to be associated with survival.Conclusion: Considering race and preexisting conditions adjusted for age in a cohort of patients with COVID -19 reveals that insurance payor is significantly associated with mortality. Those who did not have commercial or public insurance had significantly increased risk of mortality compared to those with commercial insurance.
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合并症和社会经济因素在COVID-19住院患者死亡率中的作用
背景:2019冠状病毒病作为全球大流行的出现,再次证明了种族和社会因素如何加剧健康差距,并对少数群体造成不成比例的影响。当前研究的目的是了解在大流行的第一年,这些因素如何影响俄亥俄州西北部住院的COVID-19患者的生存。方法:本研究对来自单一医疗保健系统的患者数据进行回顾性分析。查询电子病历以获取入院并在入院期间实验室确认感染COVID-19的患者的信息。不同的预测因子被纳入最终的Cox比例风险回归模型。结果:3468例患者纳入分析,全因死亡率为18.5%。平均而言,白人患者入院时年龄比黑人或“其他”种族的患者大,死亡率更高(分别为19.8%对12.5%和11.0%)。措施)。死亡率因保险状况而异,医疗保险和"其他"类别的死亡率最高(分别为27.1%和16.5%)。Cox比例风险回归模型也发现种族和保险状况与生存率相关。结论:在COVID -19患者队列中考虑种族和年龄调整后的既往病史表明,保险付款人与死亡率显着相关。与有商业保险的人相比,没有商业保险或公共保险的人死亡风险明显增加。
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