Therapy of tonsillopharyngitis: advantages of an integrated approach. A review

Sergey V. Ryazantsev, Galina S. Maltseva, Svetlana S. Vysockaya
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Abstract

The problem of pain in the pharynx continues to be the focus of attention of scientists and practitioners for many decades. Despite the emergence of modern methods of diagnosis and treatment, the problem of pharyngoalgia is far from being solved. It has now been established that more than 500 possible etiological factors can be the cause of pharyngoalgia, but the leading place is occupied by inflammatory diseases of the pharynx and palatine tonsils. Taking into account the wide distribution of this nosology among the population and the high risk of complications, especially in childhood, the issues related to the search for effective therapeutic regimens and ways to prevent the development of complications are still relevant. Definitely, the treatment should be safe, comprehensive, justified and individually selected in each case. Adequate therapy started in time allows avoiding the development of adverse effects, reducing the treatment time and improving the patient's quality of life. And for a doctor, it is extremely important to know the differences in the clinical picture of pharyngoalgia caused by different types of microorganisms: bacteria, viruses or fungal flora, since these differences will be decisive in the further tactics of treating the patient. This article is devoted to highlighting the issues of the complex use of the lysine salt of ketoprofen in local and systemic form. The parameters of the analgesic and anti-inflammatory action of the lysine salt of ketoprofen are characterized, and a new scheme for the treatment of inflammatory diseases of the pharynx within a single molecule is proposed. The article also pays attention to the prevention of complications and relapses, and discusses the advantages of the drug pidotimod in immunomodulatory therapy.
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扁桃体咽炎的治疗:综合方法的优势。回顾
咽部疼痛的问题几十年来一直是科学家和实践者关注的焦点。尽管出现了现代的诊断和治疗方法,咽痛的问题远远没有得到解决。目前已确定有500多种可能的病因可引起咽喉炎,但咽部和腭扁桃体的炎症性疾病占主导地位。考虑到这种疾病在人群中的广泛分布和并发症的高风险,特别是在儿童时期,与寻找有效的治疗方案和预防并发症发展的方法有关的问题仍然是相关的。当然,治疗应该是安全的、全面的、合理的,并在每个病例中单独选择。及时开始适当的治疗可以避免不良反应的发生,缩短治疗时间,提高患者的生活质量。对于医生来说,了解不同类型的微生物(细菌、病毒或真菌菌群)引起的咽痛的临床症状的差异是极其重要的,因为这些差异将在进一步治疗患者的策略中起决定性作用。本文致力于强调在局部和全身形式的酮洛芬赖氨酸盐的复杂使用的问题。对酮洛芬赖氨酸盐的镇痛和抗炎作用参数进行了表征,提出了单分子内治疗咽部炎症性疾病的新方案。文章还关注了并发症和复发的预防,并讨论了药物匹多莫德在免疫调节治疗中的优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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审稿时长
6 weeks
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