Effects of an Educational Package on Quality of Life and Acute Complications in Kidney Transplant Recipients: A Clinical Trial

Pegah Matourypour, Nasrin Daliri, Shahrzad Ghiyasvandian, Masoumeh Zakerimoghadam
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Abstract

Background: Patients with chronic renal failure face many challenges in self-care after a kidney transplant. This treatment method affects their quality of life and leads to multiple complications. Objectives: This study aimed to evaluate the impact of an educational package on the quality of life (QoL) and complications of renal transplant recipients. Methods: This clinical trial was conducted on 72 patients (control and intervention groups) who had undergone kidney transplantation for the first time. The intervention involved an educational package comprised of five sessions. Besides, an educational booklet, weekly telephone calls, and follow-up (8 weeks after the intervention) were protablevided. The data were collected by the Kidney Transplant Questionnaire (KTQ-25) completed before and after the intervention by the two groups, and the Renal Transplantation Complications Checklist completed after 8 weeks. Data analysis was performed in each group before and after the intervention and between the two groups after the intervention via chi-square, Fisher’s exact test, paired t-test, and independent t-test. Results: The results showed a significant difference between the intervention and control groups in the physical dimension (P = 0.002). No significant difference was observed between the two groups in the remaining dimensions and the overall QoL. A significant difference was found between the two groups in terms of infection (P = 0.04), but no difference was observed between the two groups in terms of re-admission and transplant rejection (P > 0.05). Conclusions: The educational package affected all dimensions of QoL, especially the physical dimension and infection (as an acute complication of renal transplant); it improved QoL and reduced infection in the intervention group. Therefore, this package can be considered in the management plans of renal transplant recipients. Administration of this package can help understand the patients’ needs and requests and improve their health-related behaviors.
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教育包对肾移植受者生活质量和急性并发症的影响:一项临床试验
背景:慢性肾衰竭患者在肾移植后的自我护理方面面临许多挑战。这种治疗方法影响他们的生活质量,并导致多种并发症。目的:本研究旨在评估教育包对肾移植受者生活质量(QoL)和并发症的影响。方法:对72例首次肾移植患者(对照组和干预组)进行临床试验。干预措施包括一套包括五次会议的教育方案。此外,还提供了一本教育小册子,每周电话和随访(干预后8周)。两组干预前后分别填写肾移植问卷(KTQ-25), 8周后填写肾移植并发症检查表。采用卡方检验、Fisher精确检验、配对t检验、独立t检验对干预前后各组及干预后两组间的数据进行分析。结果:干预组与对照组在体质维度上差异有统计学意义(P = 0.002)。两组在其余维度和总体生活质量方面无显著差异。两组在感染方面差异有统计学意义(P = 0.04),但在再入院和移植排斥方面差异无统计学意义(P >0.05)。结论:教育方案影响肾移植患者生活质量的各个维度,尤其是身体维度和感染(肾移植急性并发症);干预组患者生活质量提高,感染减少。因此,在肾移植受者的管理计划中可以考虑这一方案。管理这个包可以帮助了解患者的需求和要求,并改善他们的健康相关行为。
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