A Case of Pharmacologic Anisocoria in Systemic Glycopyrrolate Use from Presumed Local Ocular Inoculation

Abstract

ABSTRACTAnisocoria is a common finding in ophthalmic clinical practice. History taking and examination is critical in appropriately diagnosing and managing anisocoria, as the differential can be extensive ranging from benign to life-threatening entities. This case discusses the presentation of a 22-year-old female with a history of myopia and hyperhidrosis who presented with pharmacologic anisocoria which was presumed to be from inadvertent topical exposure to conventional glycopyrrolate tablets. To our knowledge, pharmacologic mydriasis from exposure to residue from conventional glycopyrrolate tablets has not been reported in the English literature. This case highlights the importance of medication and contact lens handling with anticholinergic agents.KEYWORDS: Anisocoriaoral glycopyrrolatemydriasisanticholinergicpharmacologic dilation Disclosure statementNo potential conflict of interest was reported by the authors.ConsentNo identifiable patient information is included. Our patient consented to the submission of this manuscript.Additional informationFundingThe authors reported there is no funding associated with the work featured in this article.