Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: Focus on Surgical Treatment Approach

Abstract

Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma (IPT-like FDC sarcomas, also known as FDC/FRC sarcoma) is a subgroup of follicular dendritic cell sarcoma (FDC), a rare neoplasm that often occurs in the spleen [1]. FDC/FRC sarcomas can affect other organs including the liver, colon, and the peripancreatic region [2-4]. The tumor has a predilection for young to middle-aged adults and may present with subset of symptoms including fever, abdominal pain, sweats, fatigue, and commonly a splenic solitary mass formation [5]. FDC/FRC sarcoma comprises of neoplastic spindle cells, typically with a follicular dendritic cell differentiation and over 90% of the cases are associated with EBV infection [6]. Here we present the a case of a IPT-like FDC sarcoma in a 49- year old female treated with splenectomy and a review of the literature.