The Urgent Need for Tungsten-Based Nanoparticles as Antibacterial Agents

Faithfulness O. Osazee, Kate E. Mokobia, Ikhazuagbe H. Ifijen
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Abstract

In recent years, the rise of antibiotic-resistant bacteria has posed a significant challenge to public health worldwide. As traditional antibiotics become less effective, there is an urgent need to explore alternative strategies to combat bacterial infections. Tungsten-based nanoparticles have emerged as promising candidates for their potential as antibacterial agents. This article highlights the pressing need for effective antibacterial agents and discusses the potential of tungsten-based nanoparticles in addressing this urgent concern. We delve into the unique properties and mechanisms of action exhibited by these nanoparticles, including their ability to generate reactive oxygen species and induce photothermal effects, leading to bacterial cell death. Additionally, we discuss the challenges associated with utilizing tungsten-based nanoparticles, such as their potential toxicity and compatibility with human cells. Furthermore, we explore the future prospects and ongoing research efforts aimed at optimizing the synthesis, characterization, and application of tungsten-based nanoparticles as antibacterial agents. By addressing these challenges and harnessing the potential of tungsten-based nanoparticles, we can pave the way for the development of effective antibacterial strategies and contribute to combating the global threat of antibiotic resistance.
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钨基纳米颗粒作为抗菌剂的迫切需要
近年来,耐抗生素细菌的增加对全球公共卫生构成了重大挑战。随着传统抗生素的效果越来越差,迫切需要探索对抗细菌感染的替代策略。钨基纳米颗粒因其作为抗菌剂的潜力而成为有希望的候选者。本文强调了对有效抗菌剂的迫切需求,并讨论了钨基纳米颗粒在解决这一紧迫问题方面的潜力。我们深入研究了这些纳米颗粒的独特性质和作用机制,包括它们产生活性氧和诱导光热效应的能力,导致细菌细胞死亡。此外,我们讨论了与利用钨基纳米颗粒相关的挑战,例如它们的潜在毒性和与人体细胞的相容性。此外,我们探讨了未来的前景和正在进行的研究工作,旨在优化钨基纳米颗粒作为抗菌剂的合成,表征和应用。通过解决这些挑战并利用钨基纳米颗粒的潜力,我们可以为开发有效的抗菌策略铺平道路,并为对抗抗生素耐药性的全球威胁做出贡献。
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