Genetic Findings in Allergic Rhinitis: A Review

Abstract

Allergic rhinitis is one of the most common diseases of the upper respiratory system, which imposes a high cost on countries every year due to its high prevalence. This disease is a global health problem. In recent years, due to the increase in prevalence and clinical importance of allergic rhinitis in other diseases, such as asthma, the study of this disease has received much attention. In this article, single nucleotide polymorphisms involved in allergic rhinitis have been studied in particular. In this study, the possible candidate genes related to allergic rhinitis in people with this disease and the single nucleotide polymorphism variants related to the said disease were investigated. The data collected in this study was the result of studies conducted in different parts of the world. The population studied in the articles are people with allergic rhinitis. The results have shown the association of several single nucleotide polymorphisms in different genes with allergic rhinitis, some of which may be useful in understanding the pathophysiology and finding new methods for immunotherapy of allergic rhinitis.