Assessment of Prescription Patterns and Appropriateness of Antibiotics for Prophylaxis in Dental Procedures: A Retrospective Study

Q3 Pharmacology, Toxicology and Pharmaceutics International Journal of Pharmaceutical Quality Assurance Pub Date : 2023-09-25 DOI:10.25258/ijpqa.14.3.45
Ashima Jakhar, Nitesh Dahiya, Amit Patil, Himmat Jaiswal, Sheetal Mali, Deepak Sharma
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Abstract

There is a lack of data on dentists’ prescribing behaviors when it comes to the correct use of antibiotics in dental treatments. Antibiotic prescriptions made by dentists were analyzed from a diagnostic perspective in a countrywide study. This study retrospectively examined national health data from January 2018 through August 2019, collected through the Prescription Information System. The analysis only included prescriptions for a single illness and at least one systemic antibiotic. Antibiotic prescribing practices and the role of dental specialization and diagnosis were studied. A total of 9,214,956 prescriptions out of 9,293,410 matched the criteria for inclusion. An average course of antibiotic treatment consists of 1.01 pills. Antibiotics were prescribed most frequently for dental caries (16.2% of cases), dental examinations (20.7% of cases), and periapical abscess without sinuses (28.1% of cases). Antibiotics were prescribed for 96.6% of patients for illogical or confusing reasons, whereas just 3.4% were given based on a single, unambiguous diagnosis, such as cellulitis or a mouth abscess. The most commonly prescribed treatment for any medical issue was amoxicillin combined with an enzyme inhibitor (58.6%). Compared to unidentified dental practitioners (58.2%; p = 0.0001), dental specialists in Groups A and B significantly overprescribed amoxicillin plus an enzyme inhibitor (67.0 and 67.8%, respectively; p = 0.0001) (data not shown). The results of the study suggest that dentists routinely and arbitrarily prescribe antibiotics with questionable rationale in the contexts studied. These results emphasize the need for dentists to begin prescribing antibiotics more deliberately and evidence-based. Educational programs, awareness campaigns, and antibiotic stewardship programmes are just some of the interventions that may be implemented to improve prescribing practices and ensure the correct use of antibiotics in dental operations. The results of this countrywide study highlight problems with dentists’ procedures for prescribing dental antibiotics. The paper states that dentists should base their prescription practices on sound reasoning and empirical data. Dentists can help with global efforts to lower antibiotic resistance and improve patient care if they prescribe them in a more reasonable and responsible manner.
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评估处方模式和适当的抗生素预防牙科程序:一项回顾性研究
在牙科治疗中正确使用抗生素方面,缺乏关于牙医开处方行为的数据。在一项全国性的研究中,从诊断的角度分析了牙医开具的抗生素处方。这项研究回顾性地检查了通过处方信息系统收集的2018年1月至2019年8月的国家卫生数据。分析只包括一种疾病的处方和至少一种全身抗生素。抗生素的处方做法和作用牙科专业化和诊断进行了研究。在9293410张处方中,符合纳入标准的处方共有9214956张。抗生素治疗的平均疗程包括1.01片。使用抗生素最多的是龋齿(16.2%)、牙科检查(20.7%)和无窦根尖周脓肿(28.1%)。96.6%的患者因为不合逻辑或令人困惑的原因开了抗生素,而只有3.4%的患者是基于单一、明确的诊断(如蜂窝织炎或口腔脓肿)开的抗生素。对于任何医疗问题,最常用的处方治疗是阿莫西林联合酶抑制剂(58.6%)。与身份不明的牙科医生相比(58.2%;p = 0.0001), A组和B组的牙科专家明显过量处方阿莫西林加酶抑制剂(分别为67.0和67.8%;P = 0.0001)(数据未显示)。研究结果表明,在研究的背景下,牙医常规和武断地开出抗生素的理由值得怀疑。这些结果强调,牙医需要开始更谨慎、更循证地开抗生素处方。教育计划、提高认识运动和抗生素管理规划只是可以实施的一些干预措施,以改善处方做法并确保在牙科手术中正确使用抗生素。这项全国性研究的结果强调了牙医开牙科抗生素处方的程序存在的问题。这篇论文指出,牙医应该把他们的处方实践建立在合理的推理和经验数据之上。如果牙医以更合理和负责任的方式开处方,他们可以帮助全球努力降低抗生素耐药性,改善患者护理。
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来源期刊
International Journal of Pharmaceutical Quality Assurance
International Journal of Pharmaceutical Quality Assurance Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
0.80
自引率
0.00%
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0
期刊介绍: INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE is a quarterly international journal publishing the finest peer-reviewed research in the field of Pharmaceutical Quality Assurance and Pharmaceutical Analysis on the basis of its originality, importance, disciplinary interest, timeliness, accessibility, elegance, and surprising conclusions. IJPQA also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
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