Antiepileptic Drugs Adverse Drug Reactions and Role of Clinical Pharmacist

Abstract

Aim: To identify the ADR of suspected adverse drugs to monitor, manage, and assess to improve patient health. Materials and Methods: The study type is a prospective observational study done in a tertiary care hospital at Telangana. Patients prescribed with at least one antiepileptic drug and patients with chronic diseases (SLE, renal and hepatic failure, etc.) were included in the study. Result: Sodium valproate shows relatively less adverse drug reactions (ADRs) (2.5%) when compared with other antiepileptics. Phenytoin shows the highest number of ADRs (50%), among which CNS-related ADRs, where more than 75% of were predictable clinical pharmacists can play a crucial role in the early identification and prevention of these ADRs due to Antiepileptic drugs.