Opiate Use Disorder and Exercise: A Systematic Review

Joseph R. Mandato, Rei Kola, Kevin Mailland, Robert W. Bales
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Abstract

Background: The opiate epidemic continues to cause hardship to American communities, including in all counties in Ohio, and resulted in 100 000 drug overdoses in 2021. Medications such as buprenorphine have helped people affected by opiate use disorder (OUD) to continue through recovery, although medication assisted therapy (MAT) has shown limited retention rates, calling for complimentary interventions to be implemented. Exercise has potential to reduce cardiovascular risk, lower obesity, and improve mental health. The aim of this study is to systematically review the literature on OUD and exercise as an adjunct to MAT. The authors hypothesize that there is a gap in the knowledge as to whether this modality has been thoroughly researched to aid in OUD recovery.Methods: A database literature search of PubMed, CINHAL, and PsychInfo returned a total of 458 abstracts. Four sets of exclusion criteria were implemented resulting in a total of 26 articles. After further review, 8 more articles were excluded by the authors.Results: Eighteen articles including participants with OUD were systematically reviewed. Only 1 article solely fo-cused on participants with OUD and exercise as an adjunct to treatment.Conclusion: Exercise as an adjunct to treatment for OUD is an area of addiction treatment that warrants further investigation. Incorporating exercise into a recovery program for people with substance use disorders (SUD) specifically has been touted as a promising modality, however, limitations in OUD only studies and lack of control groups make it difficult to draw a conclusion to support our hypothesis.
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阿片类药物使用障碍与运动:一项系统综述
背景:阿片类药物的流行继续给美国社区造成困难,包括在俄亥俄州的所有县,并在2021年导致10万例药物过量。丁丙诺啡等药物可以帮助受阿片使用障碍(OUD)影响的人继续康复,尽管药物辅助治疗(MAT)显示出有限的保留率,需要实施补充干预措施。运动有可能降低心血管风险,降低肥胖,改善心理健康。本研究的目的是系统地回顾有关OUD和运动作为MAT辅助手段的文献。作者假设,关于这种方式是否已被彻底研究以帮助OUD恢复的知识存在空白。方法:检索PubMed、CINHAL和PsychInfo数据库文献,共检索到458篇摘要。实施了四套排除标准,总共有26条。经进一步审查,又有8篇文章被作者排除。结果:系统回顾了18篇包括OUD患者的文章。只有1篇文章单独关注OUD患者并将运动作为辅助治疗。结论:运动作为OUD治疗的辅助手段是一个值得进一步研究的成瘾治疗领域。将运动纳入物质使用障碍(SUD)患者的康复计划已被吹捧为一种有前途的模式,然而,仅进行OUD研究的局限性和缺乏对照组使得很难得出支持我们假设的结论。
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