Antimicrobial resistance and its possible implications in the future: a mini review

Matrujyoti Pattnaik, Swati Pattnaik, Jyotirmayee Pradhan, Debdutta Bhattacharya
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Abstract

The emergence of antimicrobial resistance (AMR) among different species of microbes, or infectious agents, has become a major public health concern worldwide. This alarming trend is due to the rapid development of new resistance mechanisms and the decreasing effectiveness of treating common infectious diseases. As a result, standard treatments often fail to elicit a proper microbial response, leading to prolonged illness, increased healthcare costs, and a higher risk of mortality. Many infectious agents, including bacteria, fungi, viruses, and parasites, have developed high levels of multidrug resistance, resulting in increased morbidity and mortality rates, and being called as "superbugs." While the development of MDR is a natural process, it is exacerbated by the inappropriate use of antimicrobial drugs, inadequate sanitary conditions, improper food handling, and subpar infection prevention and control practices. Given the importance of AMR, this paper enlists the AMR issue along with its significance, mechanism and its possible impact in the future. The creation of innovative treatments to fight these persistent infections should be made easier by a better strategy of educating the population about the drivers of AMR.
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抗菌素耐药性及其未来可能的影响:一个小综述
不同种类微生物或感染原之间出现的抗菌素耐药性(AMR)已成为世界范围内的一个主要公共卫生问题。这一令人担忧的趋势是由于新的耐药机制的迅速发展和治疗常见传染病的有效性下降。因此,标准治疗往往不能引起适当的微生物反应,导致疾病延长,增加医疗保健费用和更高的死亡风险。许多传染性病原体,包括细菌、真菌、病毒和寄生虫,已经发展出高度的多药耐药性,导致发病率和死亡率增加,被称为“超级细菌”。虽然耐多药耐药性的发展是一个自然过程,但抗菌药物的不当使用、卫生条件不充分、食品处理不当以及不合格的感染预防和控制措施会加剧这种情况。鉴于抗菌素耐药性的重要性,本文列举了抗菌素耐药性问题及其意义、机制和未来可能产生的影响。通过更好地教育民众了解抗菌素耐药性的驱动因素,应该可以更容易地创造出对抗这些持续性感染的创新治疗方法。
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