A Case Report on Contrast Media Induced Acute Kidney Injury after Percutaneous Coronary Intervention

SP Santhosh Kumar, Shangavi V Shangavi, Reema MS Reema, Sanjana Mariam Saju, Sinta Varghese, Sneha Anna Kunjumon, Swetha Swetha D
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Abstract

Abstract: Contrast Media-Induced Nephropathy (CIN) is a well-documented phenomenon characterized by a sudden decline in renal function following the administration of contrast medium. This article presents a case study of a 58-year-old male patient who developed CIN after undergoing emergency Coronary Angiography due to Acute STEMI with RVMI. The patient’s renal parameters deteriorated rapidly, CIN is a multifaceted condition with various risk factors, including pre-existing renal impairment, diabetes mellitus, advanced age, and the use of specific medications. Its Pathogenesis involves direct Cytotoxicity, renal Vasoconstriction, and Oxidative stress. Early diagnosis is of paramount importance, relying on the detection of an increase in serum creatinine within 24 to 48 hr following contrast exposure. The management primarily revolves around hydration and the prudent avoidance of Nephrotoxic agents. This article underscores the significance of prevention strategies, which should encompass meticulous hydration, the judicious minimization of contrast usage, and the avoidance of nephrotoxic medications whenever feasible. Keywords: Contrast media, Acute kidney injury, Tubular necrosis, Vasoconstriction.
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经皮冠状动脉介入治疗后造影剂致急性肾损伤1例报告
造影剂诱导肾病(CIN)是一种有充分证据的现象,其特征是在给予造影剂后肾功能突然下降。本文报道一例58岁男性患者因急性STEMI合并RVMI接受急诊冠状动脉造影后发生CIN的病例研究。患者肾脏参数迅速恶化,CIN是一种多方面的疾病,有多种危险因素,包括预先存在的肾脏损害、糖尿病、高龄和特殊药物的使用。其发病机制包括直接的细胞毒性、肾血管收缩和氧化应激。早期诊断是至关重要的,依靠检测血清肌酐在24至48小时内增加造影剂暴露。管理主要围绕水合作用和谨慎避免肾毒性药物。这篇文章强调了预防策略的重要性,这应该包括细致的水合作用,明智地减少造影剂的使用,以及在可行的情况下避免肾毒性药物。关键词:造影剂,急性肾损伤,肾小管坏死,血管收缩
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