The analysis of the main contributing factors for the increasing trend of Diabetes Type 2, diabetes morbidity and mortality trends in England, 2017-2022.

Anzhelika Magomedova
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Abstract

Background and aim: Diabetes Type 2 is a non-communicable disease which is characterized by chronic hyperglycaemia and disruption of metabolism. A poor management of diabetes leads to serious cardiovascular and neural complications. The prevalence of Diabetes Type 2 is increasing globally; in the United Kingdom, the number of people living with a diabetes increased by more than 100,000 from 2018 to 20191. In 2019, 3,9 million people had diagnosis of diabetes, and predictions are that this number will increase to 5,3 million in 2025. The aim of this research is to examine the main contributing factors and their influence on the prevalence of Diabetes Type 2 among people aged 17+ in England based on the routine epidemiological data for 2017-2022 years. Additionally, this research will analyze trends for hospital admissions with the diagnosis of Diabetes Type 2 and diabetes mortality statistics. Methods: The Pearson’s and the Spearman’s correlation analyses are used to investigate possible associations, their strength, monotonicity and direction between the prevalence of diabetes, deprivation, low physical activity, obesity and density of fast food outlets. Stratified random sampling of 153 England counties & unitary authorities (the division of 2017) are used for the statistical analysis. A comparative analysis is used to analyze trends for hospital admissions with the diagnosis Diabetes Type 2 and diabetes mortality statistics. Descriptive statistics and quantitative analysis of secondary routine numerical data collected by the National Health Service Digital, the National Health Survey and the Office for Health Improvement & Disparities is used. Findings: The analysis revealed positive correlations between the prevalence of diabetes and indicators of deprivation, obesity, low physical activity. In general, diabetes, obesity and physically inactive adults are more prevalent in counties with higher deprivation score. The strong positive correlation was found between density of fast food outlets and deprivation; the analysis of mean values indicated a positive linear relationships between obesity, diabetes indicators and density of fast food outlets. The comparative analysis revealed an upward trend for both, hospital admissions with the diagnosis Diabetes Type 2 and diabetes mortality. Conclusion: In conclusion, analysis based on 80 counties & unitary authorities of England indicated that the main contributing factors for the increasing trend of Diabetes Type 2 can be the increasing prevalence of overweight and obese adults, low physical activity and deprivation. Additionally, the analysis demonstrated that the availability and abundance of fast food outlets, especially in more deprived deciles of England are closely associated with obesity and indirectly with the prevalence of Diabetes Type 2. Additionally, an increasing trend in the prevalence of Diabetes Type 2 is accompanied by a similar growth of hospital admissions with the diagnosis of Diabetes Type 2 and diabetes mortality.
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2017-2022年英国2型糖尿病上升趋势主要影响因素及糖尿病发病率和死亡率趋势分析
背景和目的:2型糖尿病是一种以慢性高血糖和代谢紊乱为特征的非传染性疾病。糖尿病管理不善会导致严重的心血管和神经并发症。全球2型糖尿病的患病率正在上升;在英国,从2018年到2019年,糖尿病患者人数增加了10万多。2019年,有390万人被诊断患有糖尿病,预计到2025年,这一数字将增加到530万。本研究的目的是基于2017-2022年的常规流行病学数据,研究英国17岁以上人群中2型糖尿病患病率的主要影响因素及其影响。此外,本研究将分析诊断为2型糖尿病的住院趋势和糖尿病死亡率统计。方法:采用Pearson’s和Spearman’s相关分析,探讨糖尿病患病率、贫困、低体力活动、肥胖与快餐店密度之间可能存在的关联、强度、单调性和方向性。英国153个郡的分层随机抽样统一权威机构(2017年的划分)用于统计分析。比较分析用于分析诊断为2型糖尿病的住院趋势和糖尿病死亡率统计。国家卫生服务数字化、国家卫生调查和健康改善办公室收集的二级常规数值数据的描述性统计和定量分析使用了不均衡。研究结果:分析显示,糖尿病患病率与贫困、肥胖、低运动量指标呈正相关。总体而言,糖尿病、肥胖和缺乏体育锻炼的成年人在贫困得分较高的县更为普遍。快餐店密度与贫困程度呈显著正相关;均值分析表明,肥胖、糖尿病指标与快餐店密度呈线性正相关。比较分析显示,诊断为2型糖尿病的住院人数和糖尿病死亡率都呈上升趋势。结论:最后,基于80个县的分析;英国权威机构指出,导致2型糖尿病患者增加趋势的主要因素可能是超重和肥胖成年人的患病率增加、体育活动减少和剥夺。此外,分析还表明,快餐店的可用性和丰富性,特别是在英格兰较为贫困的十分之一地区,与肥胖密切相关,并间接与2型糖尿病的患病率密切相关。此外,2型糖尿病患病率的上升趋势伴随着诊断为2型糖尿病的住院人数和糖尿病死亡率的类似增长。
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