Pregnancy in immunoglobulin A nephropathy patients; an updated review

Abstract

Immunoglobulin A nephropathy (IgAN) is found as the most frequent primary glomerulonephritis worldwide, predominantly affecting the younger population. The peak incidence of this disease occurs between the second and third decades of life, thereby making pregnancy a significant concern for women diagnosed with IgAN. Extensive studies have demonstrated that pregnancy itself does not inherently pose a specific risk for the deterioration of kidney function in individuals with IgAN who are in the initial stages of chronic kidney disease. However, it is important to note that IgAN elevates the risk of preeclampsia, a condition that is a pivotal risk factor contributing to unfavorable outcomes during pregnancy. Consequently, healthcare providers should be attentive to the potential complications of preeclampsia in pregnant women with IgAN, as its presence holds substantial implications for maternal and fetal well-being.