Pattern of Haematological and Biochemical Parameters of Dengue Virus Infection in Children

Esculapio Pub Date : 2023-08-19 DOI:10.51273/esc23.2519213
Shumaila Shahzeen, Khalid Mehmood Awan, Muhammad Azhar Farooq, Sidra Sonia Chaudhary, Mohsin Ali, Mehwish Ejaz
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Abstract

Objective: This study was conducted to study pattern of clinical, hematological and biochemical parameters in children with dengue fever. Method: A prospective comparative analysis of 120 suspected febrile children was done at social security teaching hospital in Lahore from September to November 2021. The study participants satisfying the inclusion criteria were registered for further assessment. Clinical findings were logged, hematological and biochemical parameters tests were performed. Results: In this study, there were 56.66 % male participants and 43.33 % female participants. The most common clinical manifestation was fever (100%) followed by vomiting 85.4%, abdominal pain 68.75% and body pain / myalgia in 52.08% cases. Most frequent hematological parameter wasthrombocytopenia (93.75%) followed by leucopenia 70.83% and the elevated levels of liver transaminases were seen in 68.75% subjects. Conclusion: This study focuses on the patterns of laboratory parameters of pediatric dengue viral infections .This might prove helpful for the pediatricians to suspect, diagnose and manage the dengue virus infection.
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儿童登革病毒感染血液学和生化指标的变化规律
目的:探讨登革热患儿的临床、血液学及生化指标的变化规律。方法:对2021年9 - 11月拉合尔市社会保障教学医院收治的120例疑似发热儿童进行前瞻性比较分析。符合纳入标准的研究参与者登记进行进一步评估。记录临床表现,进行血液学和生化参数测试。结果:本研究中男性参与者占56.66%,女性参与者占43.33%。最常见的临床表现为发热(100%),其次为呕吐(85.4%)、腹痛(68.75%)和躯体痛/肌痛(52.08%)。最常见的血液学指标是血小板减少(93.75%),其次是白细胞减少(70.83%)和肝转氨酶水平升高(68.75%)。结论:本研究重点探讨了小儿登革病毒感染的实验室参数变化规律,为儿科医师对登革病毒感染的怀疑、诊断和处理提供了依据。
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