Does preoperative gabapentin or intraoperative ketorolac influence postoperative pain following hip arthroscopy?

IF 1.4 4区 医学 Q3 ORTHOPEDICS Journal of Hip Preservation Surgery Pub Date : 2023-10-31 DOI:10.1093/jhps/hnad031
Alex M Meyer, Krit Petrachaianan, Natalie A Glass, Robert W Westermann
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Abstract

ABSTRACT Optimization of perioperative analgesia has important implications for patient satisfaction and short-term outcomes. This study’s purpose is to assess if preoperative gabapentin or intraoperative ketorolac influences postoperative pain or time to discharge following hip arthroscopy. In total, 409 patients who underwent hip arthroscopic femoroplasty and/or acetabuloplasty with a single surgeon for femoroacetabular impingement were retrospectively reviewed (September 2017 to February 2021). The effect of preoperative gabapentin or intraoperative ketorolac on postoperative visual analog scale (VAS) pain scores, perioperative opioids in morphine milligram equivalents (MMEs), time in post-anesthesia care unit (PACU), second-stage recovery and time to discharge was assessed using unadjusted and adjusted t-tests, and generalized linear models controlling for operative time, traction time, preoperative MME, intraoperative MME and postoperative MME were compared between the groups of gabapentin to no gabapentin and ketorolac to no ketorolac. There was no difference in first PACU VAS pain score, final PACU VAS score, VAS pain score prior to discharge, average VAS pain score or pain level on follow-up call in the unadjusted or adjusted analysis for the preoperative gabapentin or intraoperative ketorolac groups. Females had higher first PACU VAS pain score (6.05 versus 5.15 P = 0.0026), final PACU VAS pain score (4.43 versus 3.90, P = 0.0045), final VAS pain score prior to discharge (3.87 versus 3.03, P < 0.001) and average postoperative pain score (4.60 versus 4.03, P < 0.001), but no difference in VAS pain score on follow-up call following surgery. Gabapentin or ketorolac was not associated with decreased VAS pain scores or time to discharge after hip arthroscopy.
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术前加巴喷丁或术中酮咯酸是否影响髋关节镜术后疼痛?
围手术期镇痛的优化对患者满意度和短期预后具有重要意义。本研究的目的是评估术前加巴喷丁或术中酮罗拉酸是否影响髋关节镜术后疼痛或出院时间。共有409例患者接受了髋关节镜下股骨成形术和/或髋臼成形术治疗股髋臼撞击(2017年9月至2021年2月)。术前加巴喷丁或术中酮妥拉克对术后视觉模拟量表(VAS)疼痛评分、围手术期吗啡毫克当量阿片类药物(MMEs)、麻醉后护理单元(PACU)时间、第二阶段恢复和出院时间的影响采用未调整和调整t检验,并采用控制手术时间、牵引时间、术前MME、比较加巴喷丁组与不加巴喷丁组、酮罗拉酸组与不加酮罗拉酸组术中MME和术后MME的差异。术前加巴喷丁组和术中酮罗拉酸组的首次PACU VAS疼痛评分、最终PACU VAS评分、出院前VAS疼痛评分、平均VAS疼痛评分或随访时疼痛水平在未调整或调整分析中均无差异。女性患者首次PACU VAS疼痛评分(6.05比5.15 P = 0.0026)、最终PACU VAS疼痛评分(4.43比3.90,P = 0.0045)、出院前最终VAS疼痛评分(3.87比3.03,P <0.001)和术后平均疼痛评分(4.60比4.03,P <0.001),但术后随访时VAS疼痛评分无差异。加巴喷丁或酮罗拉酸与降低VAS疼痛评分或髋关节镜术后出院时间无关。
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自引率
20.00%
发文量
45
审稿时长
12 weeks
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