A rare case of a trifocal synchronous colon cancer in a 65-year old patient

Q4 Medicine Polish Annals of Medicine Pub Date : 2023-10-16 DOI:10.29089/paom/161659
Maria Krystyna Michna, Magda Bichalska-Lach, Marek Rudzki, Dariusz Waniczek
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Abstract

Introduction Colorectal cancer is one of the most common type of cancers worldwide. Simultaneous occurrence of at least two tumours in a single patient within 6 months is defined as synchronous colorectal carcinoma (SCC). Within all large intestine tumors, the occurrence of SCC is approximately 3.5%. Patients with more than two tumours account for 1.8% to 16.7% of all SCC cases. Aim We present a case of a 65-year-old female patient with triple synchronous colorectal cancer. Case study 65-year-old female patient reporting increasing fatigue and shortness of breath, lasting for 6 months, underwent preoperative colonoscopy and computed tomography (CT) scan. Both examinations indicated double malignant lesions in separate parts of the transverse colon. During the subtotal colectomy a third lesion has been found. Results and discussion The histopathology results confirmed three adenocarcinoma type tumours (two of grade 3 and one grade 2). Our patient does not suffer from any conditions that increase the probability of SCC. In her family history there are no known ancestors suffering from colon cancers or multiple primary malignant tumor. The patient does not suffer from ulcerative colitis or familial adenomatous polyposis. Conclusions The presented clinical case proves that a comprehensive pre-surgical recognition of SCC is not always possible. If a full colonoscopy is impossible, one should consider carrying out a second colonoscopy 3 months after a surgery, particularly in case of patients whose CT results are ambiguous. During a surgery, the entire length of the bowel should be palpably checked for a presence of additional tumours.
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一个罕见的病例三局灶同步结肠癌在一个65岁的病人
结直肠癌是世界上最常见的癌症之一。单个患者在6个月内同时出现至少两个肿瘤被定义为同步结直肠癌(SCC)。在所有大肠肿瘤中,SCC的发生率约为3.5%。有两个以上肿瘤的患者占所有SCC病例的1.8%至16.7%。目的报告一位65岁女性三联性结直肠癌患者。病例研究65岁女性患者报告疲劳加重和呼吸短促,持续6个月,术前进行结肠镜检查和计算机断层扫描(CT)。两项检查均显示横结肠不同部位出现双恶性病变。在结肠次全切除术中发现了第三个病变。结果和讨论组织病理学结果证实3例腺癌型肿瘤(2例3级和1例2级)。我们的患者没有任何增加SCC可能性的条件。在她的家族史中,没有已知的祖先患有结肠癌或多发性原发性恶性肿瘤。患者无溃疡性结肠炎或家族性腺瘤性息肉病。结论本临床病例证明,术前对SCC的全面识别并不总是可能的。如果无法进行完整的结肠镜检查,应考虑在术后3个月进行第二次结肠镜检查,特别是CT结果不明确的患者。在手术中,应该对整个肠道进行明显检查,以确定是否存在其他肿瘤。
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来源期刊
Polish Annals of Medicine
Polish Annals of Medicine Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
28
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