Molybdenum target X-ray examination and multimodality MRI in the diagnosis of breast cancer

IF 0.5 4区 医学 Q4 OBSTETRICS & GYNECOLOGY European journal of gynaecological oncology Pub Date : 2023-01-01 DOI:10.22514/ejgo.2023.064
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Abstract

Breast cancer is one of the most common malignant diseases, with a high mortality rate, affecting mostly females. This study aims to assess the diagnostic value of Molybdenum target X-ray examination and multimodality Magnetic Resonance Imaging (MRI) in breast cancer diagnosis. A total of 60 patients with suspected breast cancer were screened and included in the study. All patients underwent Molybdenum target X-ray and multimodality MRI, and the results were compared to pathological examination, which served as the reference standard for evaluating the diagnostic efficacy of the different screening methods. Molybdenum target X-ray examination identified 19 positive cases and 41 negative cases. Comparatively, multimodality MRI detected 43 positive cases and 17 negative cases. Compared to Molybdenum target X-ray, multimodality MRI demonstrated higher diagnostic accuracy, specificity, and sensitivity. Further analysis revealed that among the 45 positive patients, 13 were classified as stage 1, 20 as stage 2, 9 as stage 3, and 3 as stage 4. The pathological types were categorized as invasive ductal carcinoma, intraductal carcinoma, and ductal carcinoma in situ, with 25, 6 and 14 cases, respectively. Intraductal carcinoma exhibited higher levels of enhancement rate and signal enhancement ratio, as well as shorter peak time, compared to the other two types. No significant difference was observed between invasive ductal carcinoma and ductal carcinoma in situ. In the clinical diagnosis of breast cancer, multimodality MRI examination proves to be more comprehensive and accurate in determining the tumor’s nature and the type of disease, with significant clinical value in the field.
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钼靶x线检查与多模态MRI在乳腺癌诊断中的价值
乳腺癌是最常见的恶性疾病之一,死亡率高,主要影响女性。本研究旨在探讨钼靶x线检查和多模态磁共振成像(MRI)在乳腺癌诊断中的诊断价值。共有60名疑似乳腺癌患者接受了筛查,并纳入了这项研究。所有患者均行钼靶x线及多模态MRI检查,并与病理检查结果进行比较,作为评价不同筛查方法诊断效果的参考标准。钼靶x线检查阳性19例,阴性41例。多模态MRI阳性43例,阴性17例。与钼靶x线相比,多模态MRI具有更高的诊断准确性、特异性和敏感性。进一步分析显示,在45例阳性患者中,1期13例,2期20例,3期9例,4期3例。病理类型分为浸润性导管癌、导管内癌和导管原位癌,分别为25例、6例和14例。与其他两种类型相比,导管内癌表现出更高水平的增强率和信号增强比,峰值时间更短。浸润性导管癌与原位导管癌之间无显著性差异。在乳腺癌的临床诊断中,MRI多模态检查对肿瘤性质和疾病类型的判断更为全面和准确,具有重要的临床价值。
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来源期刊
自引率
25.00%
发文量
58
审稿时长
1 months
期刊介绍: EJGO is dedicated to publishing editorial articles in the Distinguished Expert Series and original research papers, case reports, letters to the Editor, book reviews, and newsletters. The Journal was founded in 1980 the second gynaecologic oncology hyperspecialization Journal in the world. Its aim is the diffusion of scientific, clinical and practical progress, and knowledge in female neoplastic diseases in an interdisciplinary approach among gynaecologists, oncologists, radiotherapists, surgeons, chemotherapists, pathologists, epidemiologists, and so on.
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