Dispersion of Hydroxyapatite Nanoparticle by Beads Milling and Its Effect on Magnetic Field Orientation

Yoshio SAKKA, Kazuya TAKAHASHI, Tetsuo UCHIKOSHI, Koji MORITA, Tohru S. SUZUKI
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Abstract

Hydroxyapatite (HAP, Ca10(PO4)6(OH)2) is a major component of bones and teeth and requires a specific crystal orientation for biomaterial applications. We have developed a method to control the orientation by applying a strong magnetic field during colloidal processing. In this study, we have demonstrated that suspensions with dispersed agglomeration-free nano particles can be produced by beads-milling HAP particles with zirconia beads as small as 0.05 mm. By slip casting in a high magnetic field and sintering using suspensions with dispersed agglomeration-free nano particles, high-density and oriented sintered bodies were successfully fabricated at low temperatures.
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珠磨法制备羟基磷灰石纳米颗粒的分散及其对磁场取向的影响
羟基磷灰石(HAP, Ca10(PO4)6(OH)2)是骨骼和牙齿的主要组成部分,在生物材料应用中需要特定的晶体取向。我们开发了一种在胶体加工过程中通过施加强磁场来控制取向的方法。在这项研究中,我们已经证明了用小至0.05 mm的氧化锆珠磨HAP颗粒可以产生具有分散的无团聚纳米颗粒的悬浮液。通过高磁场下的滑移铸造和分散无团聚的纳米颗粒悬浮液烧结,在低温下成功制备了高密度定向烧结体。
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