Inhibition of radiation induced changes in testicular RNA content by a thiophosphate.

Radiobiologia, radiotherapia Pub Date : 1989-01-01
Jaimala
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引用次数: 0

Abstract

Radiation induced changes in the testicular RNA content of whole body irradiated Swiss albino mouse and their modification by a thiophosphate, WR-2721 were studied. Three different doses of gamma radiation were given for the purpose. The RNA content of the testis was found to be affected adversely after irradiation. It was observed that the drug inhibited the alterations in the RNA content to a significant extent. Degree of protection and possible mechanisms of action have been discussed.

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硫代磷酸盐对辐射诱导睾丸RNA含量变化的抑制作用。
研究了辐射对瑞士白化病小鼠全身照射后睾丸RNA含量的影响及其硫代磷酸盐WR-2721的修饰作用。为此,研究人员使用了三种不同剂量的伽马射线。研究发现辐照后睾丸RNA含量受到不利影响。观察到该药物在很大程度上抑制了RNA含量的改变。讨论了保护程度和可能的作用机制。
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