Viscoelastic Testing on Venoarterial Extracorporeal Membrane Oxygenation: Need or Greed?

Poonam Malhotra Kapoor, Mohit Prakash, Omer Mohammed Mujahid, Mohanish Badge, T. Thiruselvan, Sanchita Garg
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Abstract

Extracorporeal life support (ECLS) is a life support modality that is being used in life-threatening cardiac and/or respiratory failure; in neonates, children, and adults. The risk of bleeding and other coagulation-related issues is unavoidable. Hence, while conducting ECLS, a patient-tailored approach is better than the generalized approach for bleeding management. There are no established guidelines for heparin use and its monitoring during ECLS in a bleeding patient on VA ECMO. Likewise, heparin and its adjuncts, though mentioned in the literature, have no consensus on what exact steps to follow in an adverse condition. Having a protocol for anticoagulation and its monitoring is of paramount importance in any center practicing ECLS. This review aims to seek the incidence of bleeding and thrombosis while on ECMO with the use of routine anticoagulant heparin and justify the need for the use of viscoelastic tests on VA ECMO.
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静脉体外膜氧合的粘弹性试验:需要还是需要?
体外生命支持(ECLS)是一种生命支持方式,用于危及生命的心脏和/或呼吸衰竭;适用于新生儿、儿童和成人。出血和其他凝血相关问题的风险是不可避免的。因此,在进行ECLS时,为患者量身定制的方法比一般的出血管理方法更好。肝素的使用和肝素监测在出血的VA ECMO患者ECLS期间没有既定的指南。同样,肝素及其辅助药物,虽然在文献中提到过,但对于在不利条件下应遵循的确切步骤尚无共识。在任何实施ECLS的中心,制定抗凝治疗方案及其监测都是至关重要的。本综述旨在探讨使用常规抗凝肝素进行ECMO时出血和血栓形成的发生率,并证明在VA ECMO中使用粘弹性试验的必要性。
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审稿时长
21 weeks
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