{"title":"Effect of hypo and hyperprolactinemia on the testicular maturation of Wistar rats during puberal transition.","authors":"M Prasad, G Uma Devi, S Govindappa","doi":"10.3109/13813458909104546","DOIUrl":null,"url":null,"abstract":"<p><p>In Wistar rats, the structural and metabolic organization of the testis was influenced by the blood concentration of prolactin. The androgen dependent enzyme activities in plasma as well as in testis were higher under hyperprolactinemia and lower under hypoprolactinemia, as induced by bromocriptine. While prolactin had direct effect on the testicular functions, bromocriptine seemed to exert its influence through blocking hypophysial prolactin.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"97 5","pages":"347-53"},"PeriodicalIF":0.0000,"publicationDate":"1989-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813458909104546","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives internationales de physiologie et de biochimie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/13813458909104546","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
In Wistar rats, the structural and metabolic organization of the testis was influenced by the blood concentration of prolactin. The androgen dependent enzyme activities in plasma as well as in testis were higher under hyperprolactinemia and lower under hypoprolactinemia, as induced by bromocriptine. While prolactin had direct effect on the testicular functions, bromocriptine seemed to exert its influence through blocking hypophysial prolactin.
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