Introduction. Rheumatoid arthritis (RA) is a systemic and chronic autoimmune disease involving the joints disorder as the main manifestations. Methotrexate (MTX) is currently still the drug of choice for RA treatment due to the good clinical response. However, there was a case reported by the American Geriatric Society in 2015 regarding the presence of reversible dementia after treatment with low-dose oral methotrexate. This study aimed to identify the effect of MTX treatment on cognitive …

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Abstract

Introduction. Doctors have greater risk of acquiring COVID-19 due to occupational exposure. Personal protective equipment (PPE) is an essential factor in reducing COVID-19 transmission. We aimed to evaluate the behavior changes of PPE usage among doctors in Indonesia before and after getting COVID-19 infection in early pandemic. Methods. This was a descriptive online survey with cross-sectional design. This survey was conducted from October-December 2020 among Indonesian doctors who were COVID-19 survivors. Results. A total of 389 doctors who survived COVID-19 infection across Indonesia were included in the final analysis. Most participants were general practitioners and residents (69.2%) with a median age of 40 (22-28) years. After being infected, there was an improvement in the use of N95 respirator masks in isolation rooms (always: 80.9% from 70.2%; sometimes: 13.2% from 15.8%). An improvement in the use of other PPE before and after being infected with COVID-19 was also shown by the use of other PPE such as headcap (93.9% from 83.3%), face shield (90.4% from 83.3%), goggles (70.2% from 62.3%), gown (61.4% from 53.6%), hazmat suit (88.6% from 81.6%), boots (82.5% from 71.1%), and gloves (91.3% from 86.8%). Similar results were also shown in the use of PPE in other non-isolation rooms. Conclusion. After recovering from COVID-19 infection, these doctors showed an increase usage of adequate PPE both while on duty in isolation and non-isolation rooms.
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介绍。类风湿性关节炎(RA)是一种以关节紊乱为主要表现的全身性慢性自身免疫性疾病。甲氨蝶呤(MTX)由于其良好的临床疗效,目前仍是治疗类风湿性关节炎的首选药物。然而,2015年美国老年病学会报告了一例低剂量口服甲氨蝶呤治疗后出现可逆性痴呆的病例。本研究旨在确定甲氨蝶呤治疗对认知功能的影响。
介绍。由于职业接触,医生感染COVID-19的风险更大。个人防护装备是减少COVID-19传播的重要因素。我们旨在评估印度尼西亚医生在COVID-19大流行早期感染前后的PPE使用行为变化。方法。这是一个横断面设计的描述性在线调查。这项调查是在2020年10月至12月期间对COVID-19幸存者的印度尼西亚医生进行的。结果。印度尼西亚共有389名在COVID-19感染中幸存下来的医生被纳入最终分析。大多数参与者为全科医生和住院医师(69.2%),中位年龄为40岁(22-28岁)。被感染后,隔离室N95口罩的使用率有所提高(总使用率从70.2%提高到80.9%;有时:从15.8%变为13.2%)。其他个人防护用品的使用情况也有所改善,如帽(从83.3%增加到93.9%)、面罩(从83.3%增加到90.4%)、护目镜(从62.3%增加到70.2%)、防护服(从53.6%增加到61.4%)、防护服(从81.6%增加到88.6%)、靴子(从71.1%增加到82.5%)和手套(从86.8%增加到91.3%)。在其他非隔离室中使用个人防护装备也显示了类似的结果。结论。从COVID-19感染中恢复后,这些医生在隔离室和非隔离室值班时都增加了适当个人防护装备的使用。
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