Submicroscopic structure of glycosaminoglycans in osteocyte capsule of human embryonic bone as revealed by polarization microscopy.

Abstract

Using qualitative and quantitative polarization microscopical techniques, an axiparallel orientation of chondroitin sulfate molecules and collagen fibrils could be detected in the osteocyte capsule of human embryonic and fetal bones. It is suggested that this spatially oriented microstructure plays a role in ana- and catabolic transport processes of the bone tissue.