Phytochemical Constituents of Cissus oliveri growing in Pwani Region, Tanzania

Fadhili S. Estomini, Stephen I. Nnungu, Amelia S. Buriyo
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Abstract

Cissus oliveri (Engl.) Gilg ex Engl. is among the plant species of the family Vitaceae widely used in traditional medicine for management of different ailments. This study aimed at assessing the phytochemicals of C. oliveri parts in order to provide scientific validation for its use as a therapeutic agent. Qualitative analysis of water and ethanolic extracts was conducted by using standard methods and the results revealed that all the parts possess alkaloids, flavonoids, phenols and tannins. Similarly, glycosides and saponins were only present in leaf and root. Quantitative analysis performed by gravimetric and spectrophotometric methods showed that all parts contain alkaloids, phenol, and tannins in large quantities. The largest amount was found in leaf for alkaloids (6.47 ± 0.41 mg/g DW) and phenols (4.85 ± 0.90 mg/g DW) compared to stem and root. Alkaloid content was higher in root than in stem (P < 0.01), whereas phenol content was the same in root and stem (p > 0.05). Further, there was no significant difference in tannins content among all the plant parts assessed. The presence and quantities of active phytochemicals in C. oliveri call for further investigations on the bioactivities of the extracts and isolated chemical constituents for potential pharmacological applications.
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坦桑尼亚Pwani地区山羊草的植物化学成分
《橄榄枝》(英文)学英语。在传统医学中被广泛用于治疗不同的疾病。本研究旨在对榄果部分的植物化学成分进行评价,为其作为治疗药物的使用提供科学依据。采用标准方法对水提液和醇提液进行定性分析,结果表明各部位均含有生物碱、黄酮类、酚类和单宁类。同样,糖苷和皂苷只存在于叶和根中。通过重量法和分光光度法进行的定量分析表明,所有部分都含有大量的生物碱、酚和单宁。与茎和根相比,叶片中生物碱(6.47±0.41 mg/g DW)和酚类物质(4.85±0.90 mg/g DW)含量最高。根中生物碱含量高于茎中(P <0.01),而根和茎中酚含量相同(p >0.05)。此外,在所有评估的植物部位之间,单宁含量没有显著差异。由于其活性化学物质的存在和含量,需要进一步研究其提取物和分离化学成分的生物活性,以开发潜在的药理应用。
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