Quantitative analysis of phenylpropanoids in Rhodiola rosea from different producing Areas

Limin Guo, Chenyang Cai, Fei Zhang, Rong Ma
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Abstract

Rhodiola (Rhodiola rosea) grows worldwide, particularly in Europe, North America and several Asia countries like China and Kazakhstan. As a functional food and medicinal herb and broadly used in healthy foods and beverages, R. rosea possesses antioxidant, antifatigue, anti-ageing, inhibitory effects of inflammation, anticancer and other pharmacological properties. More than 90 species of Rhodiola are distributed in Asia and North America, and, in particular, China is the main producing area with more than 70 species, among which R. rosea is a major one. Same as other plants, the bioactive components of R. rosea vary with growing location and conditions. Phenylpropanoids in R. rosea are a group of main bioactive phytochemicals and their contents are usually used as a quality indicator. Hence it is of great importance to characterize phenylpropanoids in R. rosea from different sources to ensure their effectiveness and efficacy. In this study, 18 R. rosea samples from Kazakhstan and 4 regions of China were collected and further characterized for their contents of rosavin, rosarin and rosin, the major biomarkers of R. rosea quality and pharmacological effects. ANOVA analysis showed significant differences among different regions. As an example, the content of total rosavins in R. rosea from Kazakhstan was more than three times that from Bazhou, Xinjiang province of China.
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不同产地红景天中苯丙素含量的定量分析
红景天(Rhodiola rosea)生长在世界各地,特别是在欧洲、北美和一些亚洲国家,如中国和哈萨克斯坦。玫瑰属功能性食品和草药,广泛应用于健康食品和饮料中,具有抗氧化、抗疲劳、抗衰老、抑制炎症、抗癌等药理作用。红景天分布在亚洲和北美有90余种,其中中国是主要产地,有70余种,其中玫瑰红景天是主要产地。与其他植物一样,玫瑰的生物活性成分随生长地点和条件的不同而变化。玫瑰红中的苯丙素是一组主要的生物活性植物化学物质,其含量通常作为玫瑰红的质量指标。因此,对不同来源的玫瑰花中苯丙素进行鉴定,对保证其药效具有重要意义。本研究收集了来自哈萨克斯坦和中国4个地区的18份玫瑰香样品,并对其质量和药理作用的主要生物标志物——玫瑰香、玫瑰香和松香的含量进行了进一步的鉴定。方差分析显示不同地区间差异显著。例如,哈萨克斯坦玫瑰红中总蔷薇素的含量是中国新疆巴州的3倍以上。
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