Sclerosing mucoepidermoid thyroid carcinoma combined with autoimmune thyroiditis

E. V. Ryabchenko
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Abstract

Background . Sclerosing mucoepidermoid thyroid carcinoma (SMTC) is a recently recognized malignant neoplasm of the thyroid. SMTC was frst reported in 1991. It arises in a background of Hashimoto thyroiditis (HT). There are two variants of mucoepidermoid carcinoma of thyroid gland: the conventional and sclerosing variants. SMTC has recently been recognized as a separate disease entity by World Health Organization (WHO). Description of the clinical case . We present the case of a 51-year-old woman with a 2-year history of autoimmune thyroiditis with a thyroid nodule. The patient had no symptoms or signs of compression. The level of thyroid–stimulating hormone (TSH) was 15.8 (range 0.4-4.0), antibodies to peroxidase: 150 Iu/ml. Scintigraphy of the thyroid gland revealed a dominant cold nodule (1.5×2 cm) in the right lobe of the gland. The control ultrasound examination showed negative fndings. Fine needle aspiration cytology of the nodule revealed follicular lesion in a background of TH. Extrafascial thyroidectomy was performed. The patient was followed up for 10 months.
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硬化性黏液表皮样甲状腺癌合并自身免疫性甲状腺炎
背景。硬化性黏液表皮样甲状腺癌(SMTC)是近年来发现的甲状腺恶性肿瘤。1991年首次报道了SMTC。它起源于桥本甲状腺炎(HT)的背景。甲状腺黏液表皮样癌有两种类型:常规型和硬化型。最近,SMTC被世界卫生组织(卫生组织)确认为一个单独的疾病实体。临床病例描述。我们提出的情况下,51岁的妇女2年历史的自身免疫性甲状腺炎甲状腺结节。患者无压迫症状或体征。促甲状腺激素(TSH) 15.8(范围0.4 ~ 4.0),过氧化物酶抗体150 Iu/ml。甲状腺显像示一显性冷结节(1.5×2 cm),位于甲状腺右叶。对照超声检查结果为阴性。结节的细针穿刺细胞学检查显示TH背景下的滤泡性病变。行筋膜外甲状腺切除术。随访10个月。
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来源期刊
Siberian journal of oncology
Siberian journal of oncology Medicine-Oncology
CiteScore
0.40
自引率
0.00%
发文量
117
审稿时长
8 weeks
期刊介绍: The main objectives of the journal are: -to promote the establishment of Russia’s leading worldwide positions in the field of experimental and clinical oncology- to create the international discussion platform intended to cover all aspects of basic and clinical cancer research, including carcinogenesis, molecular biology, epidemiology, cancer prevention, diagnosis and multimodality treatment (surgery, chemotherapy, radiation therapy, hormone therapy), anesthetic management, medical and social rehabilitation, palliative care as well as the improvement of life quality of cancer patients- to encourage promising young scientists to be actively involved in cancer research programs- to provide a platform for researches and doctors all over the world to promote, share, and discuss various new issues and developments in cancer related problems. (to create a communication platform for the expansion of cooperation between Russian and foreign professional associations).- to provide the information about the latest worldwide achievements in different fields of oncology The most important tasks of the journal are: -to encourage scientists to publish their research results- to offer a forum for active discussion on topics of major interest - to invite the most prominent Russian and foreign authors to share their latest research findings with cancer research community- to promote the exchange of research information, clinical experience, current trends and the recent developments in the field of oncology as well as to review interesting cases encountered by colleagues all over the world- to expand the editorial board and reviewers with the involvement of well-known Russian and foreign experts- to provide open access to full text articles- to include the journal into the international database- to increase the journal’s impact factor- to promote the journal to the International and Russian markets
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