The Association between Hypothermia during Emergency Room Admission and Newborn Mortality at Dr. Moewardi Hospital

Dwi Hidayah, Rinawati Rohsiswatmo, Yulidar Hafidh
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Abstract

Background: Hypothermia in newborns continues to be a significant issue and a leading cause of morbidity and mortality. The incidence of hypothermia in referral newborns is still high during hospital admission. Subjects and Method: This is a prospective cohort study conducted at Dr. Moewardi Hospital. Data collection was carried out on January 1, 2015, until March 31, 2015, for referred newborns. The dependent variable was mortality and the independent variables included gestational age, birth weight, sepsis, severe respiratory distress, and temperature at the time of admission at the ER. The chi-square test and logistic regression were used to analyze the data, with a cut-off value of p<0.05 cut off and a confidence interval of 95%. Results: There were 56 newborn referrals, with 60.7% incidence of hypothermia and 19.6% inci-dence with mortality. From the chi-square analysis, the variable of gestational age and weight did not meet the requirements of multivariate analysis (p> 0.25). The multivariate logistic regression analysis revealed a non-significant association between severe respiratory distress and mortality in referred newborns (OR= 5.25; 95% CI= 0.89 to 30.82; p= 0.066). After performing multivariate logistic regression analysis to obtain controlled ORs, there was a significant relationship between newborn referrals mortality and temperature at the time of ER admission (OR= 8.75; 95% CI= 1.07 to 3.26; p= 0.047) and sepsis (OR= 6.25; 95% CI= 150 to 28.69; p= 0.012) with mortality of referred newborns. Conclusion: The incidence of hypothermic referred newborns is high. Hypothermia during admission at the ER and sepsis are both associated with increased mortality in referred newborns. Keywords: newborns, hypothermia, mortality.
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Moewardi医生医院急诊室入院时体温过低与新生儿死亡率的关系
背景:新生儿体温过低仍然是一个重要的问题,也是发病率和死亡率的主要原因。在住院期间,转诊新生儿体温过低的发生率仍然很高。研究对象和方法:这是一项在Dr. Moewardi医院进行的前瞻性队列研究。2015年1月1日至2015年3月31日对转诊新生儿进行数据收集。因变量为死亡率,自变量包括胎龄、出生体重、败血症、严重呼吸窘迫和入院时的体温。数据分析采用卡方检验和logistic回归,截断值为p<0.05,置信区间为95%。结果:新生儿转诊56例,低体温发生率60.7%,死亡率19.6%。从卡方分析来看,胎龄和体重这两个变量不符合多变量分析的要求(p>0.25)。多因素logistic回归分析显示,转诊新生儿严重呼吸窘迫与死亡率之间无显著相关性(OR= 5.25;95% CI= 0.89 ~ 30.82;p = 0.066)。通过多变量logistic回归分析获得控制的OR,新生儿转诊死亡率与急诊室入院时的体温有显著相关(OR= 8.75;95% CI= 1.07 ~ 3.26;p= 0.047)和脓毒症(OR= 6.25;95% CI= 150 ~ 28.69;P = 0.012)与转诊新生儿的死亡率有关。结论:转诊新生儿体温过低发生率高。在急诊室入院时体温过低和败血症都与转诊新生儿死亡率增加有关。关键词:新生儿,低温症,死亡率。
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