Recent updates in nanotechnological advances for wound healing: A narrative review

IF 6.1 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Nanotechnology Reviews Pub Date : 2023-01-01 DOI:10.1515/ntrev-2023-0129
Hitesh Chopra, Yugal Kishore Mohanta, Saurov Mahanta, Tapan Kumar Mohanta, Inderbir Singh, Satya Kumar Avula, Sarada Prasanna Mallick, Ali A. Rabaan, Hajir AlSaihati, Ahmed Alsayyah, Mohammed Alissa, Hussain R. Alturaifi, Bader AlAlwan, Mohamed S. Attia, Sandip Chakraborty, Kuldeep Dhama
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Abstract

Abstract The repair and remodeling of injured tissues, known as wound healing, is a multifaceted process. The use of nanotechnology to speed up the healing process of wounds by promoting the right kind of mobility through different mechanisms has shown a lot of promise. Several nanotechnologies with novel properties have emerged in recent years, each of which targets a different issue associated with wound-healing processes. Through their antibacterial, anti-inflammatory, and angiogenic actions, nanomaterials may alter the wound microenvironment from a non-healing to a healing state. Wound dressings including hydrogels, gelatin sponges, films, and bandages may all benefit from the use of nanoparticles (NPs) to keep harmful microbes out. The addition of bioactive substances like antibiotics, NPs, and growth factors to certain dressings may further boost their efficacy. In conclusion, this review sheds light on wound healing that may be aided by the special features of materials based on nanotechnology. Although nanomaterials for wound healing show great promise, further study is needed before this promising area can convert its findings into consumer-friendly solutions.
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纳米技术在伤口愈合中的最新进展:叙述性回顾
损伤组织的修复和重塑,即伤口愈合,是一个多方面的过程。利用纳米技术通过不同的机制促进适当的移动性来加速伤口的愈合过程已经显示出很大的前景。近年来出现了几种具有新特性的纳米技术,每种纳米技术都针对与伤口愈合过程相关的不同问题。通过其抗菌、抗炎和血管生成的作用,纳米材料可以改变伤口微环境从非愈合状态到愈合状态。包括水凝胶、明胶海绵、薄膜和绷带在内的伤口敷料都可能受益于纳米颗粒(NPs)的使用,以防止有害微生物进入。在某些敷料中添加抗生素、NPs和生长因子等生物活性物质可能会进一步提高其功效。总之,这篇综述揭示了基于纳米技术的材料的特殊特性可能有助于伤口愈合。虽然纳米材料在伤口愈合方面显示出巨大的希望,但在这个有前途的领域将其发现转化为消费者友好的解决方案之前,还需要进一步的研究。
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来源期刊
Nanotechnology Reviews
Nanotechnology Reviews CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
11.40
自引率
13.50%
发文量
137
审稿时长
7 weeks
期刊介绍: The bimonthly journal Nanotechnology Reviews provides a platform for scientists and engineers of all involved disciplines to exchange important recent research on fundamental as well as applied aspects. While expert reviews provide a state of the art assessment on a specific topic, research highlight contributions present most recent and novel findings. In addition to technical contributions, Nanotechnology Reviews publishes articles on implications of nanotechnology for society, environment, education, intellectual property, industry, and politics.
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