Improvement of fine motoric movement control by elevated dosages of vitamin B1, B6, and B12 in target shooting.

D Bonke, B Nickel
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Abstract

Oral application of elevated dosages of vitamin B1, B6 and B12 have been found to improve target shooting in marksmen, recruited from a local pentathlon association, in two different studies. Study 1 was performed in an open controlled design, whereas in study 2 the group treated with B-vitamins was compared in a double-blind fashion with a placebo control group including 8 by 8 volunteers and 10 by 9 volunteers, respectively. The volunteers were randomly assigned to the groups. Performance quality was followed in both studies over a period of 8 weeks, while participants were continuously supplied with a combination of vitamins B1, B6 and B12 (Neurobion or Neurobion forte; E. Merck, Darmstadt, and Cascan, Wiesbaden, Germany). In both studies, marksmen in the vitamin-treated groups showed statistically significant, considerably improved firing accuracy as measured by the number of points achieved within a series of 20 shots at each examination. In study 2 the degree of improvement was linearly dependent on the duration of vitamin treatment, whereas the placebo-treated group, similar to the untreated control group in study 1, did not show any prominent change. Performance quality in marksmenship closely correlates with the magnitude of physiological tremor. Tremor can also be involved in the regulation quality of sensory-motor control systems. Thus, an improvement in firing accuracy as found in both studies is by the same token an improvement of fine motor control of slow movements, involving, for example, basal ganglia.(ABSTRACT TRUNCATED AT 250 WORDS)

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高剂量维生素B1、B6和B12对靶射击精细运动控制的改善。
两项不同的研究发现,口服高剂量的维生素B1、B6和B12可以改善当地五项运动协会招募的射手的射击能力。研究1采用开放对照设计,而在研究2中,服用b族维生素的组以双盲方式与安慰剂对照组进行比较,对照组分别包括8名志愿者和10名志愿者。志愿者被随机分配到不同的小组。两项研究都在8周的时间内跟踪了表现质量,同时持续向参与者提供维生素B1、B6和B12的组合(Neurobion或Neurobion forte;E. Merck, Darmstadt, and Cascan,威斯巴登,德国)。在这两项研究中,服用维生素组的射手表现出统计学上显著的提高,射击精度显著提高,这是通过每次检查中连续20次射击获得的分数来衡量的。在研究2中,改善的程度与维生素治疗的持续时间呈线性关系,而安慰剂治疗组与研究1中未治疗的对照组相似,没有表现出任何显著的变化。射击射击的表现质量与生理性震颤的大小密切相关。震颤也可能与感觉-运动控制系统的调节质量有关。因此,在两项研究中发现的射击精度的提高同样是对缓慢运动的精细运动控制的改善,例如涉及基底神经节。(摘要删节250字)
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