The role of biogenic amines in the control of blood glucose level in the decapod crustacean, Carcinus maenas L.

Comparative biochemistry and physiology. C: Comparative pharmacology Pub Date : 1993-06-01 DOI:10.1016/0742-8413(93)90210-C

Walter Lüschen, Axel Willig, Peter P. Jaros

{"title":"The role of biogenic amines in the control of blood glucose level in the decapod crustacean, Carcinus maenas L.","authors":"Walter Lüschen, Axel Willig, Peter P. Jaros","doi":"10.1016/0742-8413(93)90210-C","DOIUrl":null,"url":null,"abstract":"<div>1. Administration of biogenic amines into intact Carcinus maenas induces dose- and timedependent elevation of hemolymph glucose level.2. Removal of the neurosecretory centre containing the crustacean hyperglycemic hormone (CHH) by ablation of the eyestalks did not induce hypoglycemia.3. Injection of dopamine (DA) into eyestalkless crabs showed no hyperglycemic effect, while serotonin (5-HT), epinephrine (E), norepinephrine (NE), and octopamine (OA) elevated glucose levels.4. The dopaminergic effect was significantly reduced by administration of trifluoperazine (TFP).5. 5-HT and OA were found to be strong elevators of glucose levels, while the other biogenic amines had moderate effects only.6. The results indicate, that DA exerts its hyperglycemic effect by stimulating the release of CHH from the eyestalk neurosecretory centre. Elevation of hemolymph glucose level by 5-HT, OA, E, and NE, occurs independently of CHH.</div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"105 2","pages":"Pages 291-296"},"PeriodicalIF":0.0000,"publicationDate":"1993-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90210-C","citationCount":"77","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comparative biochemistry and physiology. C: Comparative pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/074284139390210C","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 77

Abstract

1. Administration of biogenic amines into intact Carcinus maenas induces dose- and timedependent elevation of hemolymph glucose level.

2. Removal of the neurosecretory centre containing the crustacean hyperglycemic hormone (CHH) by ablation of the eyestalks did not induce hypoglycemia.

3. Injection of dopamine (DA) into eyestalkless crabs showed no hyperglycemic effect, while serotonin (5-HT), epinephrine (E), norepinephrine (NE), and octopamine (OA) elevated glucose levels.

4. The dopaminergic effect was significantly reduced by administration of trifluoperazine (TFP).

5. 5-HT and OA were found to be strong elevators of glucose levels, while the other biogenic amines had moderate effects only.

6. The results indicate, that DA exerts its hyperglycemic effect by stimulating the release of CHH from the eyestalk neurosecretory centre. Elevation of hemolymph glucose level by 5-HT, OA, E, and NE, occurs independently of CHH.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

生物胺在控制十足甲壳类动物血糖水平中的作用。

1. 将生物胺注入完整的癌组织可诱导血淋巴葡萄糖水平呈剂量和时间依赖性升高。通过切除眼柄切除含有甲壳类高血糖激素(CHH)的神经分泌中心不会引起低血糖。3 .向无眼柄蟹注射多巴胺(DA)无高血糖作用，而血清素(5-HT)、肾上腺素(E)、去甲肾上腺素(NE)和章鱼胺(OA)使血糖水平升高。给药三氟拉嗪(TFP)显著降低了多巴胺能效应。5-羟色胺和OA被发现对血糖水平有很强的提升作用，而其他生物胺只有中等作用。结果表明，DA通过刺激眼柄神经分泌中心释放CHH来发挥其高血糖作用。5-羟色胺、OA、E和NE引起的血淋巴葡萄糖水平升高与CHH无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Comparative biochemistry and physiology. C: Comparative pharmacology

自引率

0.00%

发文量