Susceptibility of gram positive cocci to teicoplanin. Three year survey (1984-1986) at Perugia University.

M B Pasticci, F Baldelli, A Moretti, F Menichetti, S Pauluzzi
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Abstract

From 1984 to 1986, 1038 Gram positive cocci (865 Staphylococci and 173 Enterococci) have been tested for sensitivity to teicoplanin by the agar diffusion method: only one strain (Staphylococcus haemolyticus) resulted to have no zone of inhibition around the teicoplanin disk. All Staphylococcus haemolyticus strains showed higher MIC: 2.79 mcg/ml after 24h of incubation and 20.50 mcg/ml after 48h. The reduced teicoplanin sensitivity of Staphylococcus haemolyticus was not detected by the agar diffusion test.

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革兰氏阳性球菌对替柯planin的敏感性。佩鲁贾大学三年调查(1984-1986)。
从1984年到1986年,用琼脂扩散法检测了1038种革兰氏阳性球菌(865种葡萄球菌和173种肠球菌)对teicoplanin的敏感性,只有一种菌株(溶血葡萄球菌)在teicoplanin盘周围没有抑制区。所有溶血葡萄球菌菌株均表现出较高的MIC:孵育24h后为2.79 mcg/ml,孵育48h后为20.50 mcg/ml。琼脂扩散试验未发现溶血葡萄球菌对替柯普兰蛋白的敏感性降低。
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