Psychosocial interventions for people with moderate to severe dementia: A systematic review

Jonathan Boote , Vincent Lewin , Catherine Beverley , Jane Bates
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引用次数: 20

Abstract

Introduction

Psychosocial interventions are recognised as important treatments for people with dementia. Attention is now focusing on the appropriateness of such interventions for people in different stages of the illness. Two recent systematic reviews have focused on psychosocial interventions for people with a milder dementia. This systematic review investigates the effectiveness of such interventions for people with moderate to severe dementia.

Methods

A comprehensive search was undertaken using all the major health care databases, as well as various grey literature sources. For studies to be included in the review, they must have investigated the effect of one or more psychosocial intervention on people with moderate to severe dementia, employing a controlled trial design and examining outcomes such as cognitive ability, communication, functional performance, well-being, physical performance, mobility, and disruptive behaviour. Identified studies were critically appraised, and where suitable for inclusion, data were extracted.

Results

Six studies met the final inclusion criteria for the review. The included studies covered five psychosocial interventions; multi-sensory stimulation, group exercise, reality orientation, combined walking and talking, and reminiscence therapy. No evidence was found for the effectiveness of reminiscence therapy and multi-sensory stimulation. The review provides some evidence for the effectiveness of exercise in increasing muscle strength; walking and talking, in slowing the decline in mobility; and reality orientation in improving cognitive ability in the short-term.

Conclusions

This review has revealed relatively few well-designed studies focusing on the effectiveness of psychosocial interventions for people with moderate and severe dementia. This highlights the need therefore for further multi-centre randomised controlled trials to be undertaken on these interventions, together with well-designed comparative and combined studies.

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中重度痴呆患者的社会心理干预:一项系统综述
社会心理干预被认为是痴呆症患者的重要治疗方法。现在的注意力集中在对处于疾病不同阶段的人采取这种干预措施的适当性上。最近的两项系统综述侧重于对轻度痴呆症患者的社会心理干预。本系统综述调查了这些干预措施对中度至重度痴呆患者的有效性。方法利用各主要卫生保健数据库和各种灰色文献资源进行综合检索。对于纳入本综述的研究,它们必须调查一种或多种社会心理干预对中度至重度痴呆症患者的影响,采用对照试验设计,并检查认知能力、沟通、功能表现、幸福感、身体表现、活动能力和破坏性行为等结果。对确定的研究进行严格评价,并提取适合纳入的数据。结果6项研究符合最终纳入标准。纳入的研究包括五种社会心理干预措施;多感官刺激、集体练习、现实导向、走与说结合、回忆疗法。没有证据表明回忆疗法和多感觉刺激的有效性。该综述为运动在增加肌肉力量方面的有效性提供了一些证据;走路和说话,在减缓行动能力的下降;短期内以现实为导向提高认知能力。这篇综述揭示了相对较少的设计良好的研究,关注社会心理干预对中重度痴呆患者的有效性。因此,这突出表明需要对这些干预措施进行进一步的多中心随机对照试验,以及精心设计的比较和联合研究。
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