Effectiveness of 100% autologous serum drops in ocular surface disorders

Farmacia Hospitalaria (English Edition) Pub Date : 2011-01-01 DOI:10.1016/S2173-5085(11)70002-8

A. Jover Botella , J.F. Márquez Peiró , K. Márques , N. Monts Cambero , J. Selva Otaolaurruchi

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Abstract

Objective

To evaluate the effectiveness of 100% autologous serum eye drops for the treatment of various ocular surface disorders.

Methods

A descriptive prospective observational study carried out from May 2005 to February 2009 which included patients with ocular surface disorders treated with single-dose autologous serum eye drops. Treatment effectiveness was evaluated by using a clinical questionnaire in order to assess symptoms experienced by patients at the beginning and end of treatment.

Results

A total of 15 patients (24 eyes) were evaluated. Clinical symptoms such as redness, burning, sharp pain and tired eyes improved in 100% of the patients, whereas dryness and sandy/gritty sensation improved in 92% of the patients. The overall improvement of clinical symptoms was worth the inconvenience of venipuncture according to 66.7% of the patients. Regarding tolerance for autologous serum eye drops, only one patient experienced some discomfort when using the single-dose eye drops.

Conclusion

The treatment with 100% autologous serum eye drops improved ocular symptoms for most patients.

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100%自体血清滴注治疗眼表疾病的疗效

目的评价100%自体血清滴眼液治疗多种眼表疾病的疗效。方法于2005年5月至2009年2月对单剂量自体血清滴眼液治疗的眼表疾病患者进行描述性前瞻性观察研究。通过使用临床问卷来评估治疗效果，以评估患者在治疗开始和结束时经历的症状。结果共检查15例(24只眼)。100%的患者的临床症状如发红、灼烧、刺痛和眼睛疲劳得到改善，而92%的患者的干燥和沙质/砂砾感得到改善。66.7%的患者认为静脉穿刺带来的不便值得临床症状的整体改善。关于自体血清滴眼液的耐受性，只有一名患者在使用单剂量滴眼液时出现不适。结论100%自体血清滴眼液治疗多数患者眼部症状得到改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Farmacia Hospitalaria (English Edition)

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