Synchronous primary pulmonary adenocarcinoma and MALToma in a patient with Sjögren's syndrome: Case report

Abstract

The present report describes a very rare case of synchronous primary pulmonary adenocarcinoma and MALToma in a patient with Sjögren's syndrome. A 73-year-old woman with a history of Sjögren's syndrome was referred because of an abnormal shadow on X-ray. Chest radiograph revealed an irregularly shaped mass in the right lower lobe of the lung. Computed tomography showed a parenchymal lesion with an air bronchogram and spiculated contours. Chronic inflammation was seen on transbronchial lung biopsy, but clinically a pulmonary malignant tumor was suspected. No obvious abnormality other than that of the lung was detected. The patient underwent a right lower lobectomy with mediastinal lymph node dissection. The histological features of the surgical specimen were consistent with bronchiolo-alveolar carcinoma and, separately, MALT lymphoma.