Normovolemic hemodilution in head and neck surgery.

C Marchiori, A Fede, M Bassano, A Nieri
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引用次数: 2

Abstract

As the transfusion risks to which patients are exposed are gradually understood, every effort is being made to find both a valid and safe alternative to homologous blood transfusions. Bearing this in mind, the most sensible solution appears to be the practice of a self-donor procedure with normovolemic hemodilution prior to elective surgery. However, even repeated bloodlettings do not modify the oxygen delivery to tissues since, with a reduction in the hemoglobin content of the circulating blood, there is a corresponding increase in oxygen availability. Since the reduction of circulating erythrocytes brings with it a reduction in blood viscosity, there is in turn an improvement in the microcirculation. The generally better tissue oxygenation, the reduction of the blood's viscosity and the increased circulatory perfusion all also favor a prophylaxis against deep vein thrombosis. We have currently performed 72 surgical procedures for head and neck neoplasms that were undertaken at the Clinical ENT Division of Treviso Hospital precisely with the normovolemic hemodilution described above. The self-donor transfusion technique was adopted with the help of the hospital's transfusion service. We have analyzed the data relative to this method and have found that the normovolemic hemodilution represents the treatment of choice in surgery-induced stress, particularly since this approach allows a better tissue oxygenation.

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头颈部手术的等容血稀释。
随着对患者所暴露的输血风险的逐渐了解,正在尽一切努力寻找一种有效和安全的替代同源输血的方法。考虑到这一点,最明智的解决方案似乎是在择期手术前进行等容血液稀释的自体供血手术。然而,即使反复放血也不会改变组织的氧气输送,因为随着循环血液中血红蛋白含量的减少,氧气的可用性相应增加。由于循环红细胞的减少带来了血液粘度的降低,因此微循环也随之改善。通常较好的组织氧合,血液粘度的降低和循环灌注的增加也有利于预防深静脉血栓形成。目前,我们在特雷维索医院临床耳鼻喉科进行了72例头颈部肿瘤手术,采用了上述等容血液稀释法。在医院输血服务部门的帮助下,采用了自体输血技术。我们分析了与该方法相关的数据,发现等容血液稀释是手术引起的应激的治疗选择,特别是因为这种方法允许更好的组织氧合。
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