Enfermedad neurodegenerativa y suicidio

M. Gema Rodríguez Calero, Ana Belén Jiménez Galiano
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Abstract

Introduction

The conceptualization of suicidal behaviour is very complex and constitutes a worldwide health problem. Its aetiology is multifactorial and, in many cases, preventable. Suicide and neurodegenerative disease have some risk factors in common, such as depression, feelings of hopelessness and social isolation.

Objective

To find out if patients with Parkinson's disease (PD), multiple sclerosis (MS), Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and Huntington's disease (HD) are more likely to present suicidal behaviour than the general population and to ascertain the most relevant risk factors.

Method

A review of scientific articles in databases was carried out, as well as of protocols and documents published on national and government websites linking neurodegenerative disease and suicide.

Results

A clear relationship was found between suicide and MS, ALS, and HD. Results in relation to PD and AD are somewhat contradictory but a series of risk factors were detected, the presence of which could predispose individuals to this behaviour.

Conclusions

There is a greater risk of suicidal behaviour in patients with MS, ALS, and HD. We found a series of relevant risk factors associated with this behaviour, knowledge of which will help us to detect warning signs and take early action.

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神经退行性疾病和自杀
自杀行为的概念化是非常复杂的,是一个世界性的健康问题。其病因是多因素的,在许多情况下是可以预防的。自杀和神经退行性疾病有一些共同的风险因素,如抑郁、绝望感和社会孤立。目的了解帕金森病(PD)、多发性硬化症(MS)、阿尔茨海默病(AD)、肌萎缩侧索硬化症(ALS)和亨廷顿病(HD)患者是否比一般人群更容易出现自杀行为,并确定最相关的危险因素。方法对数据库中的科学文章以及在国家和政府网站上发表的有关神经退行性疾病与自杀的协议和文件进行了审查。结果自杀与多发性硬化症、ALS、HD有明显的相关性。有关PD和AD的结果有些矛盾,但检测到一系列风险因素,这些因素的存在可能使个体易患这种行为。结论:多发性硬化症、ALS和HD患者有更高的自杀行为风险。我们发现了一系列与这种行为相关的相关风险因素,了解这些因素将有助于我们发现警告信号并采取早期行动。
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18
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