[Non-specific chronic gastritis and gastric dysplasia, what is their clinical values?].

Abstract

Although nonspecific chronic gastritis and gastric dysplasia are considered as risk factors in the development of gastric cancer, the magnitude of this risk has not been well established. We made an endoscopic and histologic follow-up of 24 patients with an initial diagnosis of atrophic chronic gastritis and some degree of dysplasia over a period of 8 years. The first study revealed slight dysplasia in 8 patients, moderate dysplasia in 13 and severe dysplasia in 3. In our observation, dysplasia considered overall shows a probability of almost 54% of evolution to regression. In our study, the association of atrophic chronic gastritis and severe dysplasia is a reliable marker of gastric cancer. We think it is opportune to carry out periodic follow-ups by endoscopy and biopsy of patients with chronic gastritis and dysplasia.