Serum secretory IgA levels in patients with Behçet disease.

M Sunakawa, G Ohshio
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Abstract

Serum IgA, IgC, IgM and secretory IgA levels in patients with Behçet disease were examined. Among them, serum IgA and secretory IgA levels, which increase in mucosal inflammation, were significantly higher than controls (p less than 0.001, p greater than 0.01). These results indicate that mucosal inflammation, oral and gastrointestinal inflammation, may lead to gram-negative bacterial infection and endotoxin-induced uveitis in patients with Behçet disease.

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behet病患者血清分泌IgA水平。
检测behet病患者血清IgA、IgC、IgM及分泌IgA水平。其中,黏膜炎症升高的血清IgA和分泌IgA水平显著高于对照组(p < 0.001, p > 0.01)。这些结果表明,粘膜炎症、口腔和胃肠道炎症可能导致behet病患者的革兰氏阴性细菌感染和内毒素诱导的葡萄膜炎。
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