{"title":"Morphological aspects of lymphocyte-macrophage interactions in human tumoral effusions \"in vivo\" and \"in vitro\".","authors":"V Gotzos, B Cappelli-Gotzos","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>\"In vivo\" and \"in vitro\" morphological analysis of associations of cells (\"rosettes\") involved in immune response in human tumoral effusions revealed the existence of cell interactions either by simple membrane apposition between the cell projections or by gap-like junctions between two adjacent cells; endocytotic phenomena were also observed. The giant fibroblastic cells seen \"in vitro\" (\"myofibronoblasts\") reacting positively to anti-human macrophage Mabs, might be the cells presenting antigen to lymphocytes.</p>","PeriodicalId":75549,"journal":{"name":"Archivio italiano di anatomia e di embriologia. Italian journal of anatomy and embryology","volume":"94 3","pages":"249-55"},"PeriodicalIF":0.0000,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivio italiano di anatomia e di embriologia. Italian journal of anatomy and embryology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
"In vivo" and "in vitro" morphological analysis of associations of cells ("rosettes") involved in immune response in human tumoral effusions revealed the existence of cell interactions either by simple membrane apposition between the cell projections or by gap-like junctions between two adjacent cells; endocytotic phenomena were also observed. The giant fibroblastic cells seen "in vitro" ("myofibronoblasts") reacting positively to anti-human macrophage Mabs, might be the cells presenting antigen to lymphocytes.
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