H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai
{"title":"[Experimental study on the cleft lip and palate. VIII. Induction of cleft palate in Wistar rats by vitamin A].","authors":"H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We tried to induce cleft palate in Wistar rats by injecting Vitamin A. We injected Vitamin A into the stomach of females when they were pregnant on the eighth, ninth, tenth and eleventh day. We them sacrificed them to observe the fetuses while they were still pregnant on the eighteenth-twentieth day. The results showed that a high rate of cleft palate could be induced by injecting 5-10 x 10(4) I.U/kg of Vitamin A during pregnancy on the tenth day.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"629-34"},"PeriodicalIF":0.0000,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aichi Gakuin Daigaku Shigakkai shi","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We tried to induce cleft palate in Wistar rats by injecting Vitamin A. We injected Vitamin A into the stomach of females when they were pregnant on the eighth, ninth, tenth and eleventh day. We them sacrificed them to observe the fetuses while they were still pregnant on the eighteenth-twentieth day. The results showed that a high rate of cleft palate could be induced by injecting 5-10 x 10(4) I.U/kg of Vitamin A during pregnancy on the tenth day.
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