{"title":"Effects of cardiac rehabilitation on obese hypertensive patients: A controlled trial","authors":"H. Baykal Sahin , M. Sahin","doi":"10.1016/j.hipert.2023.05.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>The relationship between obesity and hypertension is clearly known and cardiac rehabilitation (CR) is shown as an effective treatment method in both obese and hypertensive patients. The aim of this study is to reveal the effect of CR on obese hypertensive patients by comparing them with non-obese hypertensive patients.</p></div><div><h3>Methods</h3><p>Eighty eligible, volunteer participants with hypertension (SBP ≥140<!--> <!-->mmHg and/or DBP ≥90<!--> <!-->mmHg) were enrolled in this study. The patients were divided into 2 groups according to their BMI values: obese (BMI ≥30<!--> <!-->kg/m<sup>2</sup>) hypertensive patients and non-obese (BMI <30<!--> <!-->kg/m<sup>2</sup><span>) hypertensive patients. The CR program, in which aerobic exercise training was the main part, was performed on the patients. At the end of the 10-week CR program, the resting SBP and DBP values were measured.</span></p></div><div><h3>Results</h3><p>A total of 74 patients (37 obese and 37 non-obese) completed the study. After CR significant improvements were achieved in all evaluated parameters compared to pre-CR values. When the amounts of changes before and after CR were compared, the decrease in SBP was found to be significantly higher in obese patients compared to non-obese patients (<em>p</em> <!-->=<!--> <!-->.003). Higher BMI was associated with more reduction in SBP (<em>r</em> <!-->=<!--> <!-->0.287, <em>p</em> <!-->=<!--> <!-->0.013).</p></div><div><h3>Conclusions</h3><p>Exercise-based CR effectively reduced SBP in obese and non-obese hypertensive patients. However, it was more effective in obese patients compared to non-obese patients.</p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S188918372300034X","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
The relationship between obesity and hypertension is clearly known and cardiac rehabilitation (CR) is shown as an effective treatment method in both obese and hypertensive patients. The aim of this study is to reveal the effect of CR on obese hypertensive patients by comparing them with non-obese hypertensive patients.
Methods
Eighty eligible, volunteer participants with hypertension (SBP ≥140 mmHg and/or DBP ≥90 mmHg) were enrolled in this study. The patients were divided into 2 groups according to their BMI values: obese (BMI ≥30 kg/m2) hypertensive patients and non-obese (BMI <30 kg/m2) hypertensive patients. The CR program, in which aerobic exercise training was the main part, was performed on the patients. At the end of the 10-week CR program, the resting SBP and DBP values were measured.
Results
A total of 74 patients (37 obese and 37 non-obese) completed the study. After CR significant improvements were achieved in all evaluated parameters compared to pre-CR values. When the amounts of changes before and after CR were compared, the decrease in SBP was found to be significantly higher in obese patients compared to non-obese patients (p = .003). Higher BMI was associated with more reduction in SBP (r = 0.287, p = 0.013).
Conclusions
Exercise-based CR effectively reduced SBP in obese and non-obese hypertensive patients. However, it was more effective in obese patients compared to non-obese patients.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.