Courtney E Boen, Y Claire Yang, Allison E Aiello, Alexis C Dennis, Kathleen Mullan Harris, Dayoon Kwon, Daniel W Belsky
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引用次数: 0
Abstract
Despite the prominence of the weathering hypothesis as a mechanism underlying racialized inequities in morbidity and mortality, the life course social and economic determinants of Black-White disparities in biological aging remain inadequately understood. This study uses data from the Health and Retirement Study (n = 6,782), multivariable regression, and Kitagawa-Blinder-Oaxaca decomposition to assess Black-White disparities across three measures of biological aging: PhenoAge, Klemera-Doubal biological age, and homeostatic dysregulation. It also examines the contributions of racial differences in life course socioeconomic and stress exposures and vulnerability to those exposures to Black-White disparities in biological aging. Across the outcomes, Black individuals exhibited accelerated biological aging relative to White individuals. Decomposition analyses showed that racial differences in life course socioeconomic exposures accounted for roughly 27% to 55% of the racial disparities across the biological aging measures, and racial disparities in psychosocial stress exposure explained 7% to 11%. We found less evidence that heterogeneity in the associations between social exposures and biological aging by race contributed substantially to Black-White disparities in biological aging. Our findings offer new evidence of the role of life course social exposures in generating disparities in biological aging, with implications for understanding age patterns of morbidity and mortality risks.
期刊介绍：
Since its founding in 1964, the journal Demography has mirrored the vitality, diversity, high intellectual standard and wide impact of the field on which it reports. Demography presents the highest quality original research of scholars in a broad range of disciplines, including anthropology, biology, economics, geography, history, psychology, public health, sociology, and statistics. The journal encompasses a wide variety of methodological approaches to population research. Its geographic focus is global, with articles addressing demographic matters from around the planet. Its temporal scope is broad, as represented by research that explores demographic phenomena spanning the ages from the past to the present, and reaching toward the future. Authors whose work is published in Demography benefit from the wide audience of population scientists their research will reach. Also in 2011 Demography remains the most cited journal among population studies and demographic periodicals. Published bimonthly, Demography is the flagship journal of the Population Association of America, reaching the membership of one of the largest professional demographic associations in the world.
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