[Changes in the renin-angiotensin-aldosterone system in elderly patients with chronic ischemic heart disease. 3. The renin-angiotensin-aldosterone system in elderly patients with ischemic heart disease without cardiovascular failure].

Zeitschrift fur Alternsforschung Pub Date : 1989-05-01
V Korkusko, E G Kalinovskaja, M I Fedirko, I N Gidzinskaja
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Abstract

As shown by the results of the investigation, there is a moderate rise in renin-angiotensin-aldosterone system activity in the elderly patients suffering from chronic IHK under normal conditions of life: basal level, changes in plasma renin activity and circulating aldosterone concentration during a 24-hour period and in response to the orthostasis. Considerable disturbances of the functional state of the renin-angiotensin-aldosterone system are seen with a physical load of the submaximal intensity. The data obtained indicate pathogenetic significance of the above changes which should be taken into consideration while prescribing therapy of such patients.

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老年慢性缺血性心脏病患者肾素-血管紧张素-醛固酮系统的变化。3.老年缺血性心脏病无心血管衰竭患者肾素-血管紧张素-醛固酮系统[j]。
调查结果显示,在正常生活条件下,慢性IHK老年患者肾素-血管紧张素-醛固酮系统活性中度升高:基础水平、血浆肾素活性和循环醛固酮浓度在24小时内的变化以及对直立的反应。肾素-血管紧张素-醛固酮系统功能状态的相当大的干扰可见与亚最大强度的物理负荷。所获得的数据表明上述变化的病理意义,在对此类患者进行处方治疗时应考虑到这些变化。
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