Management of neuroendocrine tumors of the rectum

Doreen Chang MD, Aurian P. García González MD, PhD, John Migaly MD
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Abstract

Rectal neuroendocrine tumors (NETs) have increased in prevalence due to increased detection via endoscopic screening for colorectal neoplasia, advances and availability of imaging tools along with the indolent nature of the tumor. Imaging techniques to identify rectal NETs include computed tomography, magnetic resonance imaging, and endoscopic rectal ultrasound. Rectal NETs are typically categorized by tumor size to determine if they should undergo endoscopic resection, local excision or transanal excision, or a radical resection, as per National Comprehensive Cancer Network guidelines. However, while examining the literature, multiple studies have examined outcomes for patients who did not adhere to these guidelines and had similar recurrence rates and survival as those patients who did. Therefore, we propose less aggressive treatment for rectal NETs in the absence of adverse features.

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直肠神经内分泌肿瘤的治疗
直肠神经内分泌肿瘤(NETs)的患病率增加,这是由于内镜下对结直肠肿瘤的筛查增加,成像工具的进步和可用性以及肿瘤的惰性性质。识别直肠NETs的成像技术包括计算机断层扫描、磁共振成像和直肠内窥镜超声。根据国家综合癌症网络指南,直肠NETs通常根据肿瘤大小进行分类,以确定是否应该进行内镜切除、局部切除或经肛门切除或根治性切除。然而,在检查文献的同时,多项研究已经检查了未遵守这些指导方针的患者的结果,并且复发率和生存率与遵守这些指导方针的患者相似。因此,我们建议在没有不良特征的情况下,对直肠NETs进行较少的积极治疗。
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
43
期刊介绍: Seminars in Colon and Rectal Surgery offers a comprehensive and coordinated review of a single, timely topic related to the diagnosis and treatment of proctologic diseases. Each issue is an organized compendium of practical information that serves as a lasting reference for colorectal surgeons, general surgeons, surgeons in training and their colleagues in medicine with an interest in colorectal disorders.
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Editorial Board Introduction Consilience of healthcare legislation, complexity science & computational analysis Artificial intelligence for the colorectal surgeon in 2024 – A narrative review of Prevalence, Policies, and (needed) Protections The impact of federally legislated colon and rectal cancer screening programs and policy in the United States
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